A nurse is providing care for four patients. Which patient should the nurse evaluate first for cognitive impairment?

Choice A rationale:
This statement is accurate. Early Lyme disease (Stage I) is typically treated with oral antibiotics for 14 to 21 days. This is often effective in clearing the infection and preventing further complications.
Choice B rationale:
This statement is also accurate. A red rash that may resemble a bull's eye is a common early symptom of Lyme disease. It often appears at the site of the tick bite, typically within 3 to 30 days after the bite.
Choice C rationale:
This statement is incorrect. While Lyme disease can be serious if not treated, it is rarely fatal. Most people who are treated for Lyme disease recover fully. However, if left untreated, it can lead to chronic health problems, such as arthritis, neurological problems, and heart issues.
Choice D rationale:
This statement is accurate. Taking precautions against tick bites is essential for preventing Lyme disease. Ticks are most active during the warmer months, so it's crucial to be vigilant about tick prevention during the spring, summer, and fall.

Choice A rationale:
Leukocyte-poor packed red blood cells (LP-PRBCs) have a significantly reduced number of white blood cells (WBCs), also known as leukocytes. This is crucial for pre-transplant patients like the one in the question for several reasons:
Prevention of Alloimmunization: WBCs in blood transfusions carry human leukocyte antigens (HLAs), which are proteins on the surface of cells that play a role in the immune system. Exposure to foreign HLAs can cause the recipient's immune system to develop antibodies against them, a process called alloimmunization. These antibodies can then attack and damage the transplanted kidney, leading to rejection. By reducing the number of WBCs in the transfusion, LP-PRBCs significantly lower the risk of alloimmunization.
Reduced Incidence of Febrile Non-Hemolytic Transfusion Reactions (FNHTRs): FNHTRs are the most common type of transfusion reaction, characterized by fever, chills, and occasionally other symptoms like nausea and vomiting. They are thought to be caused by cytokines released from WBCs in the transfused blood. LP-PRBCs, with their reduced WBC content, have been shown to lower the incidence of FNHTRs.
Potential Benefits for Graft Survival: Some studies have suggested that the use of LP-PRBCs for transfusions may improve long-term graft survival rates in kidney transplant patients, although more research is needed to confirm these findings.
Choice B rationale:
This statement is incorrect. While LP-PRBCs may have some advantages in terms of absorption or utilization, this is not the primary reason for their use in pre-transplant patients. The main goal is to reduce the risk of alloimmunization and other transfusion-related complications.
Choice C rationale:
This statement is partially correct. LP-PRBCs do tend to cause fewer blood reactions, particularly FNHTRs, as explained in the rationale for Choice A. However, this is not the most comprehensive or accurate explanation for their use in pre-transplant patients.
Choice D rationale:
This statement is not directly relevant to the use of LP-PRBCs in pre-transplant patients. While LP-PRBCs may have a lower risk of hemolysis, this is not the primary reason for their use in this specific context.