A nurse is preparing to administer erythromycin PO to a client who has an infection. The nurse checks the client's medical record and notes that the client has a severe allergy to penicillin. Which of the following actions should the nurse take?
Request a different medication from the provider
Administer the medication to the client.
Premedicate the client with diphenhydramine.
Request a different route of administration from the provider.
The Correct Answer is B
A. There is no need for change of antibiotic as there is no cross-rectivity between macrolides and penicillins.
B. Given the client's severe allergy to penicillin, it would be safe to administer erythromycin, a macrolide, as there is no risk of cross-reactivity.
C. Diphenhydramine is an antihistamine commonly used to treat allergic reactions, but premedicating the client with diphenhydramine is not necessary.
D. Changing the route of administration would not alter the risk of an allergic reaction.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
B. Maculopapular rash is a potential adverse effect of ceftriaxone. It is a type of skin rash characterized by flat, red areas (macules) and raised, bumpy areas (papules). If a client develops a rash while taking ceftriaxone, it should be reported to the healthcare provider for evaluation.

A. Constipation is not a common adverse effect of ceftriaxone. It is more commonly associated with other medications or medical conditions unrelated to ceftriaxone.
C. Pitting edema is not a common adverse effect of ceftriaxone. It may occur as a result of other medical conditions or medications, but it is not specifically associated with ceftriaxone.
D. Concentrated urine is not a common adverse effect of ceftriaxone.
Correct Answer is A
Explanation
A. Furosemide can decrease the renal clearance of lithium, leading to increased lithium levels in the blood. This can potentiate the toxic effects of lithium, such as neurotoxicity and cardiac toxicity. Therefore, concurrent use of furosemide and lithium is generally contraindicated, and caution is advised. The nurse should identify lithium carbonate as contraindicated in this scenario.
B. Albuterol is a bronchodilator commonly used to treat respiratory conditions such as asthma and chronic obstructive pulmonary disease (COPD). There are no significant contraindications between albuterol and furosemide.
C. Levothyroxine is a synthetic thyroid hormone used to treat hypothyroidism. There are no significant contraindications between levothyroxine and furosemide.
D. Cetirizine is an antihistamine used to treat allergies and allergic reactions. There are no significant contraindications between cetirizine and furosemide. They are generally considered safe to use together.
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