A nurse is preparing to administer an IV medication to a client and accidently punctures the IV bag, causing the medication to leak on the counter. Which of the following medications requires the nurse to follow facility procedures in the safe handling of a biohazardous material spill?

A. Douching is not recommended during pregnancy as it can disrupt the natural balance of vaginal flora and increase the risk of infection.
B. Loose-fitting clothing allows for better air circulation and can help prevent discomfort and irritation, especially with increased sweating and vaginal discharge during pregnancy.

C. Flat or low-heeled shoes provide better support and stability, reducing the strain on the back and pelvis, which can alleviate backaches common during pregnancy.
D. Hot showers can exacerbate itching, especially if the skin is already irritated.

Lukewarm or cool showers are preferable for relieving itching.

E. Fried foods can contribute to heartburn and indigestion, which are common during pregnancy due to hormonal changes and increased pressure on the stomach from the growing uterus.
F. An abdominal support belt can help alleviate backaches by providing additional support to the abdomen and reducing strain on the back muscles.
G. Eating frequent, smaller meals throughout the day is recommended during pregnancy to help manage heartburn, prevent overeating, and maintain stable blood sugar levels.

Rationale:

Serotonin syndrome is a serious drug reaction that results from having too much serotonin in the body. Serotonin is a chemical that plays a role in mood, sleep, appetite and other functions. Some medications, especially antidepressants, can increase serotonin levels and cause serotonin syndrome. The client is taking paroxetine, which is a type of antidepressant called a selective serotonin reuptake inhibitor (SSRI). SSRIs work by blocking the reabsorption of serotonin in the brain, making more serotonin available.

Paroxetine can cause serotonin syndrome if taken at high doses, in combination with other serotonergic drugs, or if abruptly stopped. The client’s symptoms of restlessness, abdominal pain, disorientation and fever are consistent with serotonin syndrome. Other possible symptoms include agitation, confusion, rapid heart rate, high blood pressure, dilated pupils, muscle twitching, rigidity, sweating and shivering. Severe serotonin syndrome can lead to seizures, coma and death. The client should stop taking paroxetine and seek immediate medical attention. Serotonin syndrome can be treated with supportive care and medications that reduce serotonin levels or block its effects. The client may need to switch to a different antidepressant or adjust the dosage under the guidance of their provider.