A nurse is explaining the pathophysiology of systemic inflammatory response syndrome (SIRS) to a group of newly licensed nurses. Which of the following statements by the nurse is accurate?

"A deregulated cytokine storm causes an inflammatory response."

"The major organ prone to injury during SIRS is the heart."

"Spleen dysfunction causes blood clotting issues."

"Activation of the inflammatory cascade causes increased perfusion."

Answer and Explanation

The Correct Answer is A

A. "A deregulated cytokine storm causes an inflammatory response": Systemic inflammatory response syndrome (SIRS) is characterized by a dysregulated inflammatory response triggered by various insults such as infection, trauma, burns, or ischemia. In SIRS, the immune system responds excessively, leading to the release of pro-inflammatory cytokines (cytokine storm), including tumor necrosis factor-alpha (TNF-α), interleukin-1 (IL-1), and interleukin-6 (IL-6). This cytokine cascade results in widespread inflammation and systemic manifestations, such as fever, tachycardia, tachypnea, and leukocytosis.

B. "The major organ prone to injury during SIRS is the heart": While SIRS can lead to multi-organ dysfunction, including cardiac dysfunction, it does not primarily target the heart. SIRS affects multiple organs, including the lungs, kidneys, liver, and gastrointestinal tract. Cardiac dysfunction in SIRS may result from the inflammatory response, hypoperfusion, or direct myocardial injury.

C. "Spleen dysfunction causes blood clotting issues": SIRS can lead to coagulation abnormalities, but spleen dysfunction is not the primary cause. Coagulation abnormalities in SIRS are often attributed to endothelial dysfunction, activation of the coagulation cascade, and consumption of clotting factors, rather than spleen dysfunction.

D. "Activation of the inflammatory cascade causes increased perfusion": Activation of the inflammatory cascade in SIRS does not typically lead to increased perfusion. Instead, SIRS can lead to alterations in perfusion, including tissue hypoperfusion and microvascular dysfunction. In severe cases, SIRS can progress to septic shock, characterized by profound hypotension and inadequate tissue perfusion.

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Correct Answer is C

Explanation

A. Lisinopril: Lisinopril is an angiotensin-converting enzyme (ACE) inhibitor commonly used to treat hypertension and heart failure. It is not typically contraindicated for cataract extraction surgery, and it does not significantly increase the risk of bleeding.

B. Synthroid: Synthroid is a synthetic form of thyroid hormone used to treat hypothyroidism. It does not have any direct contraindications with cataract extraction surgery and does not significantly increase the risk of bleeding.

C. Clopidogrel: Clopidogrel is an antiplatelet medication commonly used to prevent blood clots in individuals with cardiovascular diseases such as coronary artery disease or recent myocardial infarction. However, it can increase the risk of bleeding, which may be problematic during cataract extraction surgery. Therefore, it is important to question administering clopidogrel prior to the procedure and potentially coordinate with the healthcare provider regarding its management.

D. Omeprazole: Omeprazole is a proton pump inhibitor used to reduce stomach acid production and treat conditions such as gastroesophageal reflux disease (GERD) and peptic ulcer disease. It does not have any direct contraindications with cataract extraction surgery and does not significantly increase the risk of bleeding.

A. In the community, the nurse should notify emergency services. B. Compression rates and depths vary depending on the setting. C. In the hospital, codes are addressed by an interprofessional team. D. In the community, the nurse might use laypeople for assistance. E. In the community, the use of automated external defibrillators (AEDs) requires the presence of a health care provider.

Correct Answer is ["A","C","D"]

Explanation

A. In the community, the nurse should notify emergency services: In a community setting, such as outside the hospital or in a public area, it is essential to activate emergency medical services (EMS) by calling for help immediately when initiating CPR.

B. Compression rates and depths vary depending on the setting: Compression rates and depths for CPR follow standardized guidelines set by organizations such as the American Heart Association (AHA) and may not significantly differ between community and hospital settings. These guidelines typically recommend a compression rate of 100-120 compressions per minute and a compression depth of at least 2 inches (5 centimeters) for adults.

C. In the hospital, codes are addressed by an interprofessional team: In a hospital setting, cardiac arrest situations are typically addressed by an interprofessional team consisting of physicians, nurses, respiratory therapists, and other healthcare providers. This team-based approach allows for coordinated efforts in resuscitation, including advanced interventions such as airway management, medications, and defibrillation.

D. In the community, the nurse might use laypeople for assistance: In a community setting, especially if the nurse is providing CPR outside of a healthcare facility, there may be a need to involve laypeople or bystanders for assistance. Promptly recruiting bystanders to call for help, retrieve an AED if available, or assist with chest compressions can improve outcomes for the victim of cardiac arrest.

E. In the community, the use of automated external defibrillators (AEDs) requires the presence of a health care provider: In many community settings, including public places like shopping malls, airports, and schools, automated external defibrillators (AEDs) are available for use by laypeople or bystanders. While the presence of a healthcare provider is beneficial, AEDs are designed to provide audio and visual instructions for use by individuals without medical training, allowing for rapid defibrillation in cases of sudden cardiac arrest.

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A nurse is explaining the pathophysiology of systemic inflammatory response syndrome (SIRS) to a group of newly licensed nurses. Which of the following statements by the nurse is accurate?

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Naxlex Comprehensive Predictor Exams

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Correct Answer is C

Explanation

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Correct Answer is ["A","C","D"]

Explanation

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