A nurse is explaining the pathophysiology of systemic inflammatory response syndrome (SIRS) to a group of newly licensed nurses. Which of the following statements by the nurse is accurate?
"A deregulated cytokine storm causes an inflammatory response."
"The major organ prone to injury during SIRS is the heart."
"Spleen dysfunction causes blood clotting issues."
"Activation of the inflammatory cascade causes increased perfusion."
The Correct Answer is A
A. "A deregulated cytokine storm causes an inflammatory response": Systemic inflammatory response syndrome (SIRS) is characterized by a dysregulated inflammatory response triggered by various insults such as infection, trauma, burns, or ischemia. In SIRS, the immune system responds excessively, leading to the release of pro-inflammatory cytokines (cytokine storm), including tumor necrosis factor-alpha (TNF-α), interleukin-1 (IL-1), and interleukin-6 (IL-6). This cytokine cascade results in widespread inflammation and systemic manifestations, such as fever, tachycardia, tachypnea, and leukocytosis.
B. "The major organ prone to injury during SIRS is the heart": While SIRS can lead to multi-organ dysfunction, including cardiac dysfunction, it does not primarily target the heart. SIRS affects multiple organs, including the lungs, kidneys, liver, and gastrointestinal tract. Cardiac dysfunction in SIRS may result from the inflammatory response, hypoperfusion, or direct myocardial injury.
C. "Spleen dysfunction causes blood clotting issues": SIRS can lead to coagulation abnormalities, but spleen dysfunction is not the primary cause. Coagulation abnormalities in SIRS are often attributed to endothelial dysfunction, activation of the coagulation cascade, and consumption of clotting factors, rather than spleen dysfunction.
D. "Activation of the inflammatory cascade causes increased perfusion": Activation of the inflammatory cascade in SIRS does not typically lead to increased perfusion. Instead, SIRS can lead to alterations in perfusion, including tissue hypoperfusion and microvascular dysfunction. In severe cases, SIRS can progress to septic shock, characterized by profound hypotension and inadequate tissue perfusion.
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Related Questions
Correct Answer is D
Explanation
A. Lie on your back when sleeping: Lying on the back when sleeping may be recommended initially after cochlear implant surgery to avoid putting pressure on the surgical site. However, this instruction should not be included in the plan of care indefinitely. Once the client is comfortable and the surgical site is healing well, they should be allowed to sleep in any position that is comfortable for them.
B. Lie on your front when sleeping: Lying on the front when sleeping is not typically recommended after cochlear implant surgery, as it may put pressure on the surgical site and disrupt healing. This position could potentially cause discomfort and increase the risk of complications. Therefore, this instruction should not be included in the plan of care.
C. Resume your exercise routine: Resuming the exercise routine immediately after cochlear implant surgery may not be advisable. The client should be instructed to avoid strenuous activities and heavy lifting for a certain period as advised by the healthcare provider. Engaging in vigorous exercise too soon after surgery could potentially disrupt the healing process and increase the risk of complications. Therefore, this instruction should not be included in the plan of care immediately after surgery.
D. Wash your hair 24 hr after surgery: After cochlear implant insertion, it is important to keep the surgical site clean to prevent infection. Washing the hair 24 hours after surgery helps to maintain cleanliness and hygiene without disrupting the surgical site. It is typically safe to wash the hair after this period as long as gentle care is taken to avoid excessive manipulation of the implant site.
Correct Answer is C
Explanation
A. Basketball, office jobs, and listening to loud music: These activities are not typically associated with an increased risk of chronic traumatic encephalopathy (CTE). While some recreational and occupational activities may involve physical or environmental risks, they are not commonly linked to the repetitive head trauma seen in CTE.
B. Swimming, working as a nurse, and painting: These activities are not commonly associated with an increased risk of CTE. Swimming is generally a low-risk activity for head injuries, while working as a nurse and painting are not typically associated with repetitive head trauma.
C. Football, military service, and physical abuse: This is the correct answer. Chronic traumatic encephalopathy (CTE) is strongly associated with repetitive head trauma, particularly in contact sports like football, as well as in military service where blast injuries and combat-related head trauma are common. Physical abuse, especially in contact sports, can also increase the risk of CTE due to repetitive blows to the head.
D. Golfing, working in construction, and horse roping: While some occupational and recreational activities may involve a risk of head injury, they are not commonly associated with the repetitive head trauma seen in CTE. Golfing, construction work, and horse roping typically do not involve the level of repetitive head impacts seen in activities like football or military service.
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