A nurse is educating a client about a new prescription for celecoxib.
Which of the following information should the nurse include in the teaching about the medication's mechanism of action?
Inhibits histamine response.
Inhibits COX-2.
Inhibits COX-1.
Inhibits beta receptors.
The Correct Answer is B
Choice A rationale
Celecoxib does not inhibit the histamine response. Histamine is involved in allergic reactions, and celecoxib is a nonsteroidal anti-inflammatory drug (NSAID) that targets specific enzymes involved in inflammation.
Choice B rationale
Celecoxib specifically inhibits COX-2, an enzyme involved in the inflammation pathway. This selective inhibition helps reduce inflammation and pain without significantly affecting COX-1, which is protective for the stomach lining.
Choice C rationale
COX-1 is not the primary target of celecoxib. Inhibition of COX-1 can lead to gastrointestinal side effects, which celecoxib aims to minimize by selectively inhibiting COX-2 instead.
Choice D rationale
Celecoxib does not inhibit beta receptors. Beta receptors are involved in cardiovascular responses, and beta blockers are used for conditions like hypertension, not inflammation.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
Choice A rationale
Benztropine is an anticholinergic agent used to treat Parkinsonism and extrapyramidal symptoms, not suitable for reversing heparin effects.
Choice B rationale
Protamine sulfate is the specific antidote for heparin overdose. It works by neutralizing the anticoagulant effects of heparin.
Choice C rationale
Vitamin K is an antidote for warfarin overdose, promoting the synthesis of clotting factors, but ineffective against heparin.
Choice D rationale
Digibind is an antidote for digoxin toxicity, not appropriate for counteracting heparin.
Correct Answer is A
Explanation
Choice A rationale
Nifedipine is a calcium channel blocker that is effective in treating hypertension and angina. It works by relaxing the blood vessels, which lowers blood pressure and improves blood flow to the heart, reducing chest pain and hypertension.
Choice B rationale
Digoxin is not typically used to treat hypertension. It is primarily used for heart failure and atrial fibrillation to increase the strength of heart muscle contractions and regulate heart rhythm.
Choice C rationale
Heparin is an anticoagulant used to prevent and treat blood clots. It does not directly treat hypertension or angina and is used for conditions like deep vein thrombosis, pulmonary embolism, and during surgeries to prevent clot formation.
Choice D rationale
Captopril is an ACE inhibitor used to treat hypertension and heart failure. While it is effective for lowering blood pressure, it is not primarily used for treating angina compared to medications like nifedipine or other calcium channel blockers.
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