A nurse is educating a client about a new prescription for celecoxib.
Which of the following information should the nurse include in the teaching about the medication's mechanism of action?
Inhibits histamine response.
Inhibits COX-2.
Inhibits COX-1.
Inhibits beta receptors.
The Correct Answer is B
Choice A rationale
Celecoxib does not inhibit the histamine response. Histamine is involved in allergic reactions, and celecoxib is a nonsteroidal anti-inflammatory drug (NSAID) that targets specific enzymes involved in inflammation.
Choice B rationale
Celecoxib specifically inhibits COX-2, an enzyme involved in the inflammation pathway. This selective inhibition helps reduce inflammation and pain without significantly affecting COX-1, which is protective for the stomach lining.
Choice C rationale
COX-1 is not the primary target of celecoxib. Inhibition of COX-1 can lead to gastrointestinal side effects, which celecoxib aims to minimize by selectively inhibiting COX-2 instead.
Choice D rationale
Celecoxib does not inhibit beta receptors. Beta receptors are involved in cardiovascular responses, and beta blockers are used for conditions like hypertension, not inflammation.
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Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
Choice A rationale
Combining multiple hepatotoxic medications increases the risk of liver damage due to cumulative toxicity effects.
Choice B rationale
Liver damage impairs the liver's ability to metabolize medications, leading to medication accumulation and potential adverse effects.
Choice C rationale
Combining hepatotoxic medications does not decrease the risk of liver damage; it increases it, as multiple toxic agents compound the stress on the liver.
Choice D rationale
Common manifestations of hepatotoxicity include symptoms like nausea, vomiting, jaundice, dark urine, abdominal discomfort, and anorexia, indicating liver dysfunction.
Correct Answer is ["A","C","D"]
Explanation
Choice A rationale
Ethinyl estradiol and drospirenone (Yaz) is a combination oral contraceptive used to prevent pregnancy. It works by inhibiting ovulation, altering the cervical mucus to prevent sperm penetration, and changing the uterine lining to prevent implantation.
Choice B rationale
Finasteride is not used for contraception or prevention of pregnancy. It is primarily used to treat benign prostatic hyperplasia (BPH) and androgenetic alopecia (male pattern baldness).
Choice C rationale
Desogestrel (Mirena) is a hormonal intrauterine device (IUD) used for long-term contraception. It releases a progestin hormone that thickens cervical mucus, inhibits sperm motility, and thins the endometrial lining to prevent pregnancy.
Choice D rationale
Medroxyprogesterone acetate (Depo-Provera) is an injectable contraceptive that provides long-term prevention of pregnancy. It prevents ovulation and thickens cervical mucus to inhibit sperm penetration.
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