A nurse is discussing intravenous Amphotericin B treatment with a nursing student who is about to care for a patient with a systemic fungal infection. Which statement by the student indicates a need for further teaching?

Choice A reason:
The onset of warfarin is delayed, meaning it takes longer to achieve a therapeutic effect. Warfarin requires several days to adjust to effective anticoagulation levels because it works by inhibiting the synthesis of clotting factors that are already present and active in the bloodstream. In contrast, heparin has an immediate anticoagulant effect when administered, which is crucial for patients with acute conditions like deep vein thrombosis.

Choice B reason:
Warfarin does not prevent platelet aggregation. Instead, it works by inhibiting vitamin K-dependent clotting factors, which are essential for blood coagulation. Platelet aggregation is primarily inhibited by antiplatelet drugs like aspirin or clopidogrel, not anticoagulants like warfarin.

Choice C reason:
Heparin does not necessarily have fewer adverse effects compared to warfarin. Both anticoagulants have their specific risks and side effects. Heparin is preferred in acute settings due to its rapid onset of action, but it can cause complications like heparin-induced thrombocytopenia (HIT), which requires careful monitoring.

Choice D reason:
Heparin does not have a longer half-life than warfarin. In fact, heparin's half-life is relatively short, which is why it is often administered via continuous infusion or frequent subcutaneous injections. Warfarin has a longer half-life, but its delayed onset of action makes it less suitable for immediate anticoagulation needs.

Choice A reason:
An embolus is the term used to describe a detached blood clot or other material that travels through the bloodstream and can cause a blockage in a blood vessel. Emboli can be composed of blood clots, fat, air, or other substances, and they can lead to serious conditions like strokes or pulmonary embolisms when they obstruct blood flow.

Choice B reason:
A thrombus is a blood clot that forms in a blood vessel and remains at its site of origin. It does not refer to a clot that has detached and is traveling through the bloodstream. The distinction between thrombus and embolus is crucial in understanding and describing vascular conditions.

Choice C reason:
Thromboembolus is a term that combines thrombus and embolus, indicating that a thrombus has become an embolus. While accurate, the more precise and commonly used term for a detached blood clot is simply "embolus."

Choice D reason:
Infarction refers to tissue death due to a lack of blood supply, often caused by an embolus or thrombus blocking a blood vessel. It does not describe the detached blood clot itself but rather the result of its action.