Which modes of transmission occur with HIV infection? (Select all that apply)

Choice A reason:
Vitamin K (phytonadione) is the antidote for warfarin overdose. It works by promoting the synthesis of clotting factors that are inhibited by warfarin, thereby reversing the anticoagulant effects. In cases of excessive warfarin intake, administering vitamin K helps restore normal clotting function.

Choice B reason:
Protamine sulfate is the antidote for heparin overdose, not warfarin. It works by neutralizing the anticoagulant effects of heparin, but it has no effect on warfarin-induced anticoagulation. Therefore, it is not appropriate for this situation.

Choice C reason:
A PTT lab test measures the effectiveness of the intrinsic pathway of coagulation and is primarily used to monitor heparin therapy. It is not relevant for managing warfarin overdose, as warfarin affects the extrinsic pathway, which is measured by the PT/INR test.

Choice D reason:
While an INR lab test is essential for monitoring the therapeutic levels of warfarin, the immediate need in this situation is to reverse the effects of the overdose. Administering vitamin K is the necessary intervention to counteract the excessive anticoagulation caused by warfarin.

Choice A reason:
Decreased afterload due to vasodilation is not the primary cause of hypotension in acute myocardial infarction. While vasodilation can lower blood pressure, in the context of MI, the more direct and significant cause of hypotension is the reduced cardiac contractility leading to decreased cardiac output. Vasodilation and afterload reduction are not the primary mechanisms in this scenario.

Choice B reason:
A rapid heart rate, or tachycardia, can contribute to hypotension by reducing the time for the heart to fill with blood between beats. However, in the context of an acute myocardial infarction, the primary issue is the heart's ability to contract effectively. Therefore, while a rapid heart rate might exacerbate the condition, it is not the main cause of hypotension.

Choice C reason:
Decreased cardiac contractility, resulting in decreased cardiac output, is the primary cause of hypotension in acute myocardial infarction. The damaged heart muscle cannot pump effectively, leading to reduced blood flow and low blood pressure. This is a direct consequence of the myocardial damage caused by the infarction, making this the correct answer.

Choice D reason:
Increased capillary permeability is not a primary cause of hypotension in acute myocardial infarction. This condition is more associated with inflammatory responses, sepsis, or allergic reactions. The main cause of hypotension in MI is related to the heart's reduced pumping ability.