A nurse is collecting data from a client who has Cushing’s syndrome. Which of the following findings should the nurse expect?

Choice A: “I will feel shaky.” This is a correct statement, as shakiness is a common manifestation of hypoglycemia, which is a low blood glucose level. Hypoglycemia can cause the sympathetic nervous system to release adrenaline, which can cause tremors, nervousness, and anxiety.

Choice B: “My skin will be warm and moist.” This is an incorrect statement, as warm and moist skin is not a typical manifestation of hypoglycemia. Warm and moist skin can be a sign of hyperglycemia, which is a high blood glucose level. Hyperglycemia can cause dehydration, which can lead to sweating and flushing.

Choice C: “I will be more thirsty than usual.” This is an incorrect statement, as thirst is not a typical manifestation of hypoglycemia. Thirst can be a sign of hyperglycemia, which can cause dehydration, as the body tries to flush out excess glucose through urine.

Choice D: “My appetite will be decreased.” This is an incorrect statement, as decreased appetite is not a typical manifestation of hypoglycemia. Decreased appetite can be a sign of other conditions, such as nausea, infection, or depression. Hypoglycemia can cause increased hunger, as the body needs more glucose to function properly.

Choice A reason: Weight loss is not a symptom of Cushing’s syndrome. On the contrary, weight gain and obesity are common signs of this condition, especially in the trunk, face and upper back1.

Choice B reason: Diaphoresis, or excessive sweating, is not a symptom of Cushing’s syndrome. It can be caused by other conditions, such as hyperthyroidism, menopause or anxiety.

Choice C reason: Hyperpigmentation, or darkening of the skin, is a symptom of Cushing’s syndrome. It occurs due to increased production of melanin, the pigment that gives color to the skin. Hyperpigmentation can affect any part of the body, but it is more noticeable in areas exposed to friction or pressure, such as the elbows, knees, knuckles and armpits.

Choice D reason: Hypotension, or low blood pressure, is not a symptom of Cushing’s syndrome. In fact, high blood pressure (hypertension) is one of the common symptoms of this condition, due to the effects of cortisol on the cardiovascular system.