A nurse is collecting data from a client who has been taking carbamazepine. Which of the following is an adverse effect of carbamazepine and should be reported to the provider?

A. Celecoxib is contraindicated in individuals with a history of hypersensitivity reactions, including anaphylaxis, angioedema, or urticaria, to sulfonamides. Sulfonamide antibiotics are structurally related to sulfonamide nonantibiotics, including celecoxib, and cross-sensitivity reactions may occur in some individuals.
B. Penicillin allergy is not a contraindication for celecoxib. There is no cross-reactivity between penicillin antibiotics and celecoxib, as they are different classes of medications.
C. Concurrent use of chondroitin is not a contraindication for celecoxib. Chondroitin is a dietary supplement commonly used for joint health, and there are no known interactions or contraindications between chondroitin and celecoxib.
D. Concurrent use of calcium supplements is not a contraindication for celecoxib. There are no known interactions between calcium supplements and celecoxib, and they can be safely used together if indicated.

A. Increased respiratory rate is a sign that naloxone is effectively reversing opioid-induced respiratory depression. Opioids can suppress the respiratory drive, leading to hypoventilation or respiratory arrest. Naloxone works by competitively binding to opioid receptors and displacing opioids, thereby restoring normal respiratory function.
B. Increased temperature is not a direct effect of naloxone administration. Naloxone primarily reverses the central nervous system depressant effects of opioids, including respiratory depression and sedation, rather than affecting body temperature.
C. Naloxone does not directly affect pain perception. Its primary action is to reverse the respiratory depression and central nervous system depression caused by opioids. While the client may experience pain relief indirectly as a result of improved respiratory function and consciousness, naloxone itself does not directly reduce pain.
D. Decreased blood pressure is not a direct effect of naloxone administration. Naloxone primarily reverses the respiratory and central nervous system depressant effects of opioids, rather than affecting blood pressure directly.