A nurse is caring for a client who is to start taking cyclosporine following a kidney transplant. The nurse should instruct the client that which of the following foods can have an adverse interaction with this medication?
Grapefruit juke
Pepperoni
Smoked salmon
Orange juice
The Correct Answer is A
Cyclosporine is an immunosuppressant medication that is often used following organ transplant to prevent rejection. Grapefruit juice can increase the absorption of cyclosporine, leading to an increased risk of side effects and toxicity. Therefore, clients taking cyclosporine should be advised to avoid grapefruit and grapefruit juice while taking this medication. Pepperoni and smoked salmon do not have any known interactions with cyclosporine. Orange juice may also interact with cyclosporine, but not to the same extent as grapefruit juice. It is generally recommended that clients taking cyclosporine avoid drinking large amounts of orange juice and to inform their healthcare provider if they experience any adverse effects.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
Vancomycin is a glycopeptide antibiotic that is effective against gram-positive bacteria, particularly against MRSA, which is resistant to other antibiotics like methicillin. It is not effective against gram-negative bacteria such as Pseudomonas aeruginosa and Klebsiella. Candida is a fungal infection and is not treated with vancomycin. Therefore, in this educational program, the nurse manager should emphasize that vancomycin is indicated for the treatment of infections caused by MRSA.
Correct Answer is B
Explanation
The correct answer is choiceb. Monitor the serum medication levels.
Choice A rationale:
Administering gentamicin with food is not necessary and does not minimize the risk of adverse effects. Gentamicin is typically given intravenously or intramuscularly, and food does not impact its administration or absorption.
Choice B rationale:
Monitoring the serum medication levels is crucial when administering gentamicin. Gentamicin has a narrow therapeutic index, meaning the difference between a therapeutic dose and a toxic dose is small. Regular monitoring helps ensure the drug remains within the safe and effective range, reducing the risk of nephrotoxicity and ototoxicity.
Choice C rationale:
Limiting the client’s fluid intake is not recommended. Adequate hydration is important to help prevent nephrotoxicity, a known adverse effect of gentamicin. Ensuring the client has sufficient fluid intake can help protect kidney function.
Choice D rationale:
Instructing the client to report agitation is not directly related to minimizing the risk of adverse effects of gentamicin. While it is important for clients to report any unusual symptoms, agitation is not a common adverse effect of gentamicin. Monitoring for signs of nephrotoxicity (e.g., decreased urine output) and ototoxicity (e.g., hearing loss, tinnitus) is more relevant.
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