A nurse is caring for a client who is diagnosed with schizophrenia. Which of the following manifestations should the nurse identify as a negative symptom?

C. Agranulocytosis is a serious side effect associated with clozapine, an antipsychotic medication. Agranulocytosis is characterized by a severe reduction in the number of white blood cells (specifically granulocytes) in the bloodstream, leading to an increased risk of infection. The client should be educated to monitor for signs and symptoms of agranulocytosis, including sore throat, fever, chills, and muscle aches, as these may indicate an underlying infection due to neutropenia.

A. Severe restlessness may be a side effect of some antipsychotic medications, but it is not specifically associated with agranulocytosis.

B. Respiratory depression and a comatose state are not typical manifestations of agranulocytosis.

D. Increased anxiety and suicidal ideations may be symptoms of certain mental health conditions or adverse effects of psychiatric medications, but they are not characteristic of agranulocytosis.

A. This demonstrates honesty, integrity, and accountability, which are important qualities in a healthcare professional. It also allows the nurse to ensure that the information provided is accurate and reliable, rather than providing potentially incorrect or misleading information.

B. Asking the community member to hold their question until the end may not be necessary and could potentially discourage further engagement.

C. This may disrupt the flow of the presentation and could inconvenience other attendees. Admitting not knowing the answer and committing to follow up may be a more efficient approach.

D. Providing an inaccurate or speculative answer when unsure may lead to misinformation and erode trust with the community members.