A nurse is caring for a client who has HIV-I infection and is prescribed zidovudine as part of antiretroviral therapy. The nurse should monitor the client for Which of the following adverse effects of this medication?
Renal failure
Metabolic alkalosis
Aplastic anemia
Cardiac dysrhythmia
The Correct Answer is C
Zidovudine (AZT) is an antiretroviral drug used in treatment of HIV to suppress viral replication. It causes aplastic anemia, suppression of the bone marrow, leasing to reduces production of all hematopoietic cell lines including red blood cells, white blood cells, and platelets.
A, B, and D - are not associated with Zidovudine use
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
Montelukast is a leukotriene receptor antagonist used for the long-term control of asthma. Among the side effects, montelukast causes drowsiness and hence should be taken at night before bed to avoid interference with daily activities.
A. Montelukast is an oral preparation that does not require a spacer unlike inhalers such as salbutamol
B. Montelukast is used controller therapy rather than a reliever in acute asthmatic attack
D. Rinsing the mouth is relevant in the use of inhaled corticosteroids to prevent oral thrush but not montelukast.
Correct Answer is B
Explanation
Methotrexate is immunomodulatory that inhibits DNA synthesis and repair but blocking the metabolism of DNA building blocks. In addition to it disease modifying effects on targeted tissues, it also affects rapidly dividing cells such as the bone marrow leading to reduced platelets that causes bleeding. Information on number of platelets is important to guide the next action
A-Electric brush will worsen the bleeding
C-This is important but not priority as the bleeding is likely related to the medication
D- Explaining is important but does not address the issue at hand
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