A nurse is caring for a client who has HIV-I infection and is prescribed zidovudine as part of antiretroviral therapy. The nurse should monitor the client for Which of the following adverse effects of this medication?
Renal failure
Metabolic alkalosis
Aplastic anemia
Cardiac dysrhythmia
The Correct Answer is C
Zidovudine (AZT) is an antiretroviral drug used in treatment of HIV to suppress viral replication. It causes aplastic anemia, suppression of the bone marrow, leasing to reduces production of all hematopoietic cell lines including red blood cells, white blood cells, and platelets.
A, B, and D - are not associated with Zidovudine use
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Related Questions
Correct Answer is B
Explanation
A. The symptoms described (flushing and tachycardia) are not indicative of an anaphylactic reaction, which typically includes symptoms like difficulty breathing, hives, or swelling. Documenting it as an anaphylactic reaction would be misleading and could lead to inappropriate management.
B. Slowing the infusion rate can help mitigate the symptoms of Red Man Syndrome, which is often related to the rate of vancomycin administration. The recommended infusion rate for vancomycin is generally over at least 60 minutes, and reducing the rate can help alleviate symptoms.
C. Applying cold compresses should help with pain but as important like documentation.
D. The infusion should be continued and not used again for the client.
Correct Answer is C
Explanation
Rationale- Glipizide is an oral hypoglycemic agent. It belongs to a class of drugs referred to as sulfonyl ureas. It acts on the beta cells of the pancreases to stimulate release of insulin. This helps the body in lowering blood glucose levels appropriately.
A. Glipizide help in lowering blood sugars after carbohydrate metabolism, it does not directly absorb excess carbohydrates in the system.
B. Glipizide has no effect on the liver
D. Glipizide stimulates the pancreas to release more insulin but not to replace- it is not an insulin
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