A nurse is caring for a client who has been diagnosed with thrombotic thrombocytopenic purpura (TTP) and will begin plasmapheresis ment should the nurse plan to include when educating the client about this treatment?
we excess ADAMTS-13 from your plasma
large von Willebrand factor molecules from your plasma
macrophages from your spleen
performed once a week until your platelet counts normalize.
The Correct Answer is B
A. Plasmapheresis in TTP aims to remove abnormal blood components, not ADAMTS-13. In fact, plasmapheresis helps replenish ADAMTS-13.
B. The primary goal of plasmapheresis in TTP is to remove large von Willebrand factor molecules that are causing platelet aggregation and clot formation.
C. Removing macrophages from the spleen is not the objective of plasmapheresis.
D. Plasmapheresis is usually performed daily until clinical and laboratory parameters improve, not just once a week.
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Related Questions
Correct Answer is D
Explanation
A. Romiplostim does not increase the production of ADAMTS-13; it is used to increase platelet counts.
B. Romiplostim does not prevent platelet destruction in the spleen; it works by stimulating platelet production.
C. Romiplostim does not prevent platelets from binding with heparin; it is not used for heparin-induced thrombocytopenia.
D. Romiplostim is a thrombopoietin receptor agonist that stimulates the bone marrow to increase platelet production, which is its primary mechanism of action in treating ITP.
Correct Answer is ["24"]
Explanation
To calculate the IV pump rate, you'll need to use the formula: (Ordered amount of medication (units/hr) × Volume of fluid in mL) / Amount of medication in the volume = IV pump rate in mL/hr. For the given scenario, the ordered amount is 1,200 units/hr, the volume of fluid is 500 mL, and the amount of medication in the volume is 25,000 units. Plugging these numbers into the formula gives you: (1,200 units/hr × 500 mL) / 25,000 units = 24 mL/hr. Therefore, the nurse should set the IV pump to deliver 24 mL/hr.
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