A nurse is assessing a client who has severe preeclampsia and is receiving magnesium sulfate via continuous IV infusion.

Which of the following findings should alert the nurse to suspect magnesium toxicity?

Administer calcium gluconate as an antidote if toxicity occurs.Magnesium sulfate is a mineral that reduces seizure risks in women with severe preeclampsia.However, it can also cause side effects and toxicity, such as respiratory depression, muscle weakness, and cardiac arrest.Calcium gluconate is an antidote that can reverse the effects of magnesium sulfate and restore normal neuromuscular function.

Choice B is wrong because magnesium sulfate does not affect blood glucose levels.

There is no need to monitor the client’s blood glucose level every 4 hours.

Choice C is wrong because the infusion should be discontinued if the client’s respiratory rate is below 12/min, not 16/min.

A low respiratory rate indicates respiratory depression, which is a sign of magnesium toxicity.

Choice D is wrong because the infusion rate should not be increased if the client’s urine output is above 30 mL/hr.Urine output should be at least 30 mL/hr while administering magnesium sulfate to prevent accumulation of the drug in the body.

Increasing the infusion rate can increase the risk of toxicity.

The correct answer is choice A and E. The nurse should check the client’s blood pressure and magnesium level before giving hydralazine to a client with severe pre-eclampsia who is receiving magnesium sulfate intravenously.

• Choice A is correct because hydralazine is an antihypertensive drug that lowers blood pressure by relaxing blood vessels.The nurse should monitor the client’s blood pressure before and after giving hydralazine to ensure that it is within the target range and to avoid hypotension or rebound hypertension.

• Choice B is wrong because pulse oximetry is not directly related to hydralazine administration or pre-eclampsia.Pulse oximetry measures the oxygen saturation of hemoglobin in the blood and can be affected by factors such as anemia, hypothermia, nail polish, or movement.

The nurse should monitor the client’s pulse oximetry as part of routine care, but it is not a priority before giving hydralazine.

• Choice C is wrong because checking the client’s reflexes is not directly related to hydralazine administration or pre-eclampsia.Reflexes are assessed to monitor for signs of magnesium toxicity, which can cause muscle weakness, respiratory depression, and cardiac arrest.

The nurse should check the client’s reflexes as part of routine care, but it is not a priority before giving hydralazine.

• Choice D is wrong because checking the client’s urine specific gravity is not directly related to hydralazine administration or pre-eclampsia.Urine specific gravity measures the concentration of solutes in the urine and can be affected by factors such as hydration status, renal function, or diuretic use.

The nurse should monitor the client’s urine specific gravity as part of routine care, but it is not a priority before giving hydralazine.

• Choice E is correct because magnesium sulfate is a drug that prevents and treats seizures in women with severe pre-eclampsia or eclampsia.The nurse should monitor the client’s magnesium level before and after giving magnesium sulfate to ensure that it is within the therapeutic range and to avoid magnesium toxicity.