A nurse is administering medications to a client who weighs 132 lb. The prescription reads chloramphenicol, 50mg/kg/day in 4 divided doses. Available is chloramphenicol 100 mg/mL. How many mL should the nurse give with each dose? (Round the answer to the nearest tenth. Use a leading zero if it applies. Do not use a trailing zero.)

Answer and Explanation

The Correct Answer is ["7.5"]

Convert the client's weight from pounds to kilograms. We can use the formula 1 kg = 2.2 lb. So, 132 lb / 2.2 = 60 kg.

Calculate the total daily dose of chloramphenicol for the client. We can use the formula Dose (mg) = Weight (kg) x Dosage (mg/kg). So, 60 kg x 50 mg/kg = 3000 mg.

Divide the total daily dose by 4 to get the dose for each administration. So, 3000 mg / 4 = 750 mg.

Calculate the volume of chloramphenicol solution needed for each dose. We can use the formula Volume (mL) = Dose (mg) / Concentration (mg/mL). So, 750 mg / 100 mg/mL =

7.5 mL.

Round the answer to the nearest tenth. So, the nurse should give 7.5 mL of chloramphenicol solution with each dose.

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Correct Answer is C

Explanation

A. Laryngospasm: Laryngospasm is not a commonly associated adverse effect of alteplase administration. It is more commonly associated with airway irritants or allergic reactions.
B. Polycythemia: Polycythemia, or an abnormally high red blood cell count, is not a typical adverse effect of alteplase administration. Alteplase is a thrombolytic agent used to dissolve blood clots and is not associated with increasing red blood cell production.

C. Hemorrhage: Hemorrhage, or bleeding, is the most significant adverse effect associated with alteplase administration. Alteplase works by promoting fibrinolysis and can increase the risk of bleeding, including intracranial hemorrhage, particularly in the context of thrombolytic therapy for stroke.
D. Steatorrhea: Steatorrhea, or fatty stools, is not a commonly associated adverse effect of alteplase administration. It is more commonly associated with malabsorption disorders or pancreatic insufficiency.

A. Hypomagnesemia B. Hypocalcemia C. Hyponatremia D. Hypokalemia

Correct Answer is C

Explanation

A. Hypomagnesemia: While lithium can affect magnesium levels, starting a new exercise program is not typically associated with hypomagnesemia. Hypomagnesemia may result in muscle weakness, tremors, and cardiac dysrhythmias.
B. Hypocalcemia: Starting a new exercise program is not typically associated with hypocalcemia. Hypocalcemia may present with muscle cramps, tetany, and seizures.
C. Hyponatremia: Starting a new exercise program may lead to dehydration and electrolyte imbalances, including hyponatremia (low sodium levels). This can have profound effects on patients taking lithium. Symptoms of hyponatremia include weakness, confusion, and seizures.
D. Hypokalemia is not a common occurrence among individuals doing exercise.

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Naxlex Comprehensive Predictor Exams

A nurse is caring for a client who received alteplase 12 hr ago following a thrombotic stroke. The nurse should monitor the client for which of the following adverse effects?

Correct Answer is C

Explanation

A nurse is caring for a client who is taking lithium and reports starting a new exercise program. The nurse should assess the client for which of the following electrolyte imbalances?

Correct Answer is C

Explanation

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