A group of nursing students are reviewing antineoplastic drugs.
The students demonstrate understanding of the information when they identify which of the following as cell cycle specific?

Alkylating agents.

Plant alkaloids.

Antineoplastic antibiotics.

Retinoids.

Answer and Explanation

The Correct Answer is B

Choice A rationale:

Alkylating agents. Alkylating agents are not cell cycle-specific. These agents work by directly binding to DNA and interfering with the cell's ability to replicate and divide. Their action is not limited to a specific phase of the cell cycle, making them non-cell cycle-specific agents. Alkylating agents are often used in cancer chemotherapy to prevent cell division and growth.

Choice C rationale:

Antineoplastic antibiotics. Antineoplastic antibiotics are not cell cycle-specific either. These drugs, such as doxorubicin and bleomycin, work by disrupting DNA and RNA synthesis and are used to treat various types of cancer. However, they do not specifically target cells in a particular phase of the cell cycle.

Choice D rationale:

Retinoids. Retinoids are not cell cycle-specific antineoplastic agents. Retinoids are compounds related to vitamin A and are used for various medical purposes, including some cancer treatments. However, their mechanism of action is not tied to a specific phase of the cell cycle, making them non-cell cycle-specific.

Choice B rationale:

Plant alkaloids. Plant alkaloids, such as vinca alkaloids (vincristine and vinblastine) and taxanes (paclitaxel), are considered cell cycle-specific antineoplastic drugs. These agents interfere with microtubule function, which is critical during mitosis (cell division). By disrupting microtubules, they specifically target rapidly dividing cancer cells during the M phase of the cell cycle. This selectivity for actively dividing cells makes plant alkaloids cell cycle-specific antineoplastic drugs.

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Correct Answer is D

Explanation

Choice A rationale:

Hypertension is not a medical condition that contraindicates the use of ginger for digestive purposes. Ginger is often considered safe for individuals with hypertension when used in moderation.

Choice B rationale:

Kidney stones are not directly related to the use of ginger for digestion. Ginger is generally safe for consumption, and there is no known link between ginger and the formation of kidney stones.

Choice C rationale:

Vitamin B12 deficiency, while important, is not a condition that specifically contraindicates the use of ginger for digestion. However, individuals with vitamin B12 deficiency may need to address the underlying issue with appropriate treatment.

Choice D rationale:

Before advising the client to take ginger to aid with digestion, the nurse should ensure that the client does not have liver disease. Ginger can impact liver function, and individuals with liver disease may need to avoid or limit its use. This precaution is important to prevent any adverse effects on the liver in vulnerable individuals.

A. An increase in seizure activity. B. Signs of vitamin B12 deficiency. C. Increased absorption of iron. D. Signs of folate deficiency.

Correct Answer is C

Explanation

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A group of nursing students are reviewing antineoplastic drugs.The students demonstrate understanding of the information when they identify which of the following as cell cycle specific?

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Naxlex Comprehensive Predictor Exams

At a yearly physical examination, a client asks the nurse if it would be okay to take ginger to aid with digestion.Before telling the client it is okay to take ginger, which medical conditions should the nurse make sure the client does not have?

Correct Answer is D

Explanation

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Correct Answer is C

Explanation

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A group of nursing students are reviewing antineoplastic drugs.
The students demonstrate understanding of the information when they identify which of the following as cell cycle specific?