A nurse is providing care to a client receiving highly active antiretroviral therapy (HAART). The nurse would expect the client to receive which of the following antiretroviral agents?
Nonprotease inhibitors.
Nonnucleoside reverse transcriptase inhibitors.
Entry inhibitors.
Integrase inhibitors.
The Correct Answer is D
Choice A rationale:
Nonprotease inhibitors are not typically a part of HAART (Highly Active Antiretroviral Therapy). Protease inhibitors are used to inhibit HIV replication.
Choice B rationale:
Nonnucleoside reverse transcriptase inhibitors (NNRTIs) are often used in HAART, but they are not the primary agents responsible for inhibiting the integration of the viral genome into the host cell's DNA. NNRTIs target the reverse transcriptase enzyme.
Choice C rationale:
Entry inhibitors are another class of antiretroviral drugs, but they work by blocking the entry of the virus into host cells, not by inhibiting integration. They are used in combination with other drugs in specific cases.
Choice D rationale:
Integrase inhibitors are a class of antiretroviral drugs that specifically target the enzyme integrase, which is responsible for integrating the viral genome into the host cell's DNA. This choice is correct because integrase inhibitors are a crucial component of HAART and help prevent the virus from replicating in the host's cells.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
Correct Answer is A
Explanation
Choice A rationale:
Protease inhibitors are a category of antiretroviral drugs used in the treatment of HIV. They work by affecting an enzyme called protease, which is necessary for the maturation of new viral particles. By inhibiting protease, these drugs prevent the formation of mature, infectious HIV particles.
Choice B rationale:
Reverse transcriptase inhibitors, including both nucleoside and non-nucleoside variants, target the enzyme reverse transcriptase. This enzyme is involved in the conversion of HIV RNA into DNA, an essential step in the viral life cycle. However, it's not about preventing the maturation of new viral particles, as mentioned in the question.
Choice C rationale:
Nonnucleoside reverse transcriptase inhibitors (NNRTIs) also inhibit the reverse transcriptase enzyme, but they do so differently than protease inhibitors. While they are vital in HIV treatment, they do not specifically target the maturation of viral particles.
Choice D rationale:
Integrase inhibitors target the enzyme integrase, which is involved in the integration of viral DNA into the host cell's DNA. This step is crucial in the HIV life cycle, but it's not related to the maturation of new viral particles.
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