A client with chronic kidney disease has chronic anemia. What pharmacologic alternative to blood transfusion may be used for this patient?
Erythropoietin (Epogen)
Eltrombopag (Promacta)
GM-CSF (Leukine)
Thrombopoietin (TPO)
The Correct Answer is A
A. Erythropoietin (Epogen):
Explanation: Erythropoietin is a hormone that stimulates the production of red blood cells. In chronic kidney disease, especially when associated with anemia, the production of erythropoietin by the kidneys may be reduced. Erythropoietin (Epogen) is commonly used to stimulate the production of red blood cells and manage anemia in patients with chronic kidney disease.
B. Eltrombopag (Promacta):
Explanation: Eltrombopag is a medication used to stimulate the production of platelets and is primarily indicated for conditions associated with thrombocytopenia (low platelet count). It is not used to treat anemia associated with chronic kidney disease.
C. GM-CSF (Leukine):
Explanation: Granulocyte-macrophage colony-stimulating factor (GM-CSF or Leukine) is a medication that stimulates the production of white blood cells and is used in certain conditions to address decreased white blood cell counts. It is not typically used for managing anemia.
D. Thrombopoietin (TPO):
Explanation: Thrombopoietin is a hormone that stimulates the production of platelets. Medications that mimic the action of thrombopoietin, such as romiplostim and eltrombopag, are used to treat thrombocytopenia. Thrombopoietin is not used for the treatment of anemia.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
A. It is rapidly absorbed, has a fast onset of action:
Explanation: This statement is incorrect. Glargine (Lantus) actually has a slow onset of action and a prolonged duration of action. It is formulated to provide a steady level of insulin in the body over an extended period.
B. Administer the total daily dosage in two doses:
Explanation: This is not the recommended administration for glargine. It is typically administered once daily to provide basal insulin coverage over a 24-hour period.
C. Draw up the drug first, then add regular insulin:
Explanation: Mixing glargine with other insulins is not recommended. Glargine should be administered separately to maintain its extended duration of action. It should not be mixed with other insulins in the same syringe.
D. Do not mix with other insulins:
Explanation: This is the correct statement. Glargine should not be mixed with other insulins. It should be administered alone to maintain its "peakless" basal coverage. Mixing it with other insulins could alter its pharmacokinetics and compromise its effectiveness.
Correct Answer is ["C","E"]
Explanation
A. Asthma:
Explanation: Asthma is associated with respiratory alkalosis, not respiratory acidosis. In asthma, there is often hyperventilation leading to a decrease in carbon dioxide levels.
B. Hyperventilation:
Explanation: Correct. Hyperventilation can cause respiratory alkalosis, not respiratory acidosis. It leads to a decrease in carbon dioxide levels.
C. Chronic obstructive pulmonary disease (COPD):
Explanation: Correct. Conditions like COPD can lead to respiratory acidosis. In COPD, there is impaired ventilation, leading to an accumulation of carbon dioxide.
D. Renal insufficiency:
Explanation: Renal insufficiency is not a direct cause of respiratory acidosis. Respiratory acidosis is primarily related to respiratory system dysfunction.
E. Pneumonia:
Explanation: Correct. Pneumonia can cause respiratory acidosis. In pneumonia, there may be difficulty in eliminating carbon dioxide due to impaired gas exchange.

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