A client with advanced cirrhosis has been admitted to the medical-surgical unit. The nurse is assessing the client and identifies which of the following findings as indicators of hepatic encephalopathy? (Select all that apply).

Choice A reason:

A headache is not typically an indication of an allergy to nitroglycerin. Allergic reactions are more likely to present with symptoms such as rash, itching, or difficulty breathing.

Choice B reason:Headaches are a well-known side effect of nitroglycerin, due to its vasodilating effects, which can cause dilation of cerebral arteries.

Choice C reason:While anxiety can cause headaches, in this context, where the client has taken nitroglycerin, it is more likely that the headache is a side effect of the medication rather than anxiety.

Choice D reason:Tolerance to medication would reduce the effectiveness of the drug, not typically cause a headache. The headache is a common side effect, not an indication of tolerance.

Choice A reason: Hypophosphatemia refers to an abnormally low level of phosphate in the blood. The normal range for serum phosphate in adults is typically around 2.5 to 4.5 mg/dL. In the context of acute kidney injury (AKI), the kidneys’ ability to excrete phosphate is impaired, which can actually lead to hyperphosphatemia, not hypophosphatemia. Therefore, while phosphate levels are important to monitor in AKI, hypophosphatemia is not typically expected.

Choice B reason: Hypercalcemia is characterized by an elevated level of calcium in the blood, with the normal range being approximately 8.5 to 10.2 mg/dL. AKI can sometimes be associated with hypercalcemia, particularly if there is extensive tissue breakdown or rhabdomyolysis. However, it is not as commonly expected as hyperkalemia. Hypercalcemia in AKI is more often secondary to other underlying conditions rather than a direct result of the kidney injury itself.

Choice C reason: Hyperkalemia is a common electrolyte imbalance in AKI and refers to a high level of potassium in the blood. The normal range for serum potassium is about 3.5 to 5.0 mEq/L. In AKI, the kidneys’ ability to excrete potassium is compromised, leading to an accumulation of potassium in the blood. This can be life-threatening, causing cardiac dysrhythmias and muscle weakness. Hyperkalemia is a key concern in AKI management and is often expected in this condition. While all the listed electrolyte imbalances can occur in various clinical scenarios, hyperkalemia is the most commonly expected electrolyte disturbance in a patient with acute kidney injury. It is crucial for healthcare providers to monitor and manage electrolyte levels carefully in AKI to prevent complications.

Choice D reason: Hypernatremia means an elevated sodium level in the blood, with the normal range being 135 to 145 mEq/L. While sodium balance can be affected in AKI, hypernatremia is not typically expected. It is more commonly associated with conditions that cause a loss of water or an intake of sodium, such as diabetes insipidus or excessive salt ingestion. In AKI, the focus is often on managing fluid overload rather than sodium excess.