A nurse is caring for a client who has a pulmonary embolism and has a new prescription for enoxaparin 1.5 mg/kg/dose subcutaneously every 12 hours. The client weighs 245 lbs. How many mg should the nurse administer per dose? (Round the answer to the nearest whole number. Use a leading zero if it applies. Do not use a trailing zero.)

Choice A Reason: This is incorrect because cognitive impairment that decreases over several months post-injury is more likely to occur in a client who has a diffuse axonal injury, which is a widespread damage to the brain's white mater.

Choice B Reason: This is incorrect because neurologic deficits that increase up to 2 weeks post-injury are more likely to occur in a client who has a subdural hematoma, which is a collection of blood between the dura and the arachnoid membranes.

Choice C Reason: This is incorrect because a change in the level of consciousness that develops over 48 hr is more likely to occur in a client who has an intracerebral hematoma, which is a collection of blood within the brain tissue.

Choice D Reason: This is correct because a lucid period followed by an immediate loss of consciousness is a typical manifestation of an epidural hematoma, which is a collection of blood between the skull and the dura. The lucid period occurs when the initial bleeding stops and the client regains consciousness. The immediate loss of consciousness occurs when the bleeding resumes and causes increased intracranial pressure.

Choice A Reason: This choice is incorrect because slowing the rate to 50 mL/hr may not be enough to prevent cerebral edema, which is a common complication of head injury. Cerebral edema is a swelling of the brain tissue due to increased fluid accumulation. It can cause increased intracranial pressure (ICP), which can lead to brain damage or death. Therefore, the nurse should limit the fluid intake of the client with head injury to avoid worsening the condition.

Choice B Reason: This choice is incorrect because increasing the rate to 250 mL/hr may cause fluid overload, which can also increase the ICP and worsen the cerebral edema. Fluid overload is a condition in which the body has too much fluid, which can impair the function of the heart, lungs, and kidneys. Therefore, the nurse should avoid giving too much fluid to the client with head injury.

Choice C reason: Reducing the infusion to 20 mL/hr is excessively low and may cause hypotension or inadequate maintenance of vascular access and medication delivery. Such a drastic decrease could impair perfusion to injured brain tissue and is not an appropriate independent nursing action without a specific order.

Choice D reason: Maintaining the current prescribed infusion rate avoids abrupt volume shifts that could alter intracranial pressure. The nurse should monitor neurologic status and vital signs, ensure the IV is patent, and follow provider orders; only change the rate when clinically indicated or when directed by the prescriber.