A client with a history of schizophrenia, and drug and alcohol abuse is admitted to the hospital for hepatitis. The nurse should contact the healthcare provider before implementing which prescription?
Acetaminophen 650 mg PO PRN.
Olanzapine 30 mg PO at bedtime.
Thiamine, USP 100 mg PO daily.
Ondansetron 8 mg IV PRN.
The Correct Answer is A
Choice A reason: Acetaminophen is hepatotoxic, metabolized by the liver via cytochrome P450 to NAPQI, which depletes glutathione, causing necrosis in hepatitis. A compromised liver from alcohol or viral hepatitis increases toxicity risk, even at standard doses. Contacting the provider ensures safer analgesics, preventing further liver damage in this high-risk client.
Choice B reason: Olanzapine, an antipsychotic, manages schizophrenia by blocking dopamine D2 receptors. It is metabolized by the liver but has low hepatotoxicity risk compared to acetaminophen in hepatitis. No immediate contraindication exists, as it controls psychosis without significantly worsening liver function, making it safe to administer without delay.
Choice C reason: Thiamine (vitamin B1) is essential in hepatitis, particularly with alcohol abuse, preventing Wernicke’s encephalopathy from deficient glucose metabolism. It is liver-safe and beneficial, supporting neurological function without toxicity. Administering thiamine is appropriate, making it unnecessary to contact the provider before implementation.
Choice D reason: Ondansetron, an antiemetic, controls nausea in hepatitis via serotonin 5-HT3 receptor blockade. It is metabolized by the liver but has minimal hepatotoxicity, safe in liver disease. No contraindication exists, as it alleviates symptoms without worsening hepatitis, unlike acetaminophen, which poses significant liver risk.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
Choice A reason: Thick, dry, dark areas on heels suggest chronic skin changes, not early pressure ulcers. Persistent redness over bone is the earliest sign (Stage 1). This indicates later damage, per pressure injury staging and prevention protocols in nursing care for immobile clients.
Choice B reason: Broken skin indicates a Stage 2 pressure ulcer, beyond the earliest stage. Persistent redness (Stage 1) signals initial tissue compromise. Broken skin requires intervention but is not the earliest sign, per pressure ulcer assessment and prevention standards in nursing practice.
Choice C reason: Persistent redness over bone is the earliest sign of a Stage 1 pressure ulcer, indicating tissue compromise due to pressure. Early intervention prevents progression in bedrest clients with heart failure, per pressure injury prevention and skin assessment protocols in nursing care.
Choice D reason: A superficial sacral ulcer (Stage 2) is more advanced than persistent redness (Stage 1), the earliest sign. Redness allows earlier intervention to prevent ulceration. Ulcers indicate progression, per pressure ulcer staging and prevention guidelines for immobile clients in nursing.
Correct Answer is C
Explanation
Choice A reason: Elevating the hand reduces edema, potentially improving circulation, but is premature without assessing the absent radial pulse’s cause. Post-fracture, compartment syndrome or arterial injury risks ischemia. Neurovascular assessment identifies severity, guiding targeted interventions to restore perfusion, making elevation secondary to assessment.
Choice B reason: Measuring blood pressure and heart rate provides systemic data but not localized insight into the absent radial pulse, likely from arterial compression post-surgery. Neurovascular assessment evaluates limb perfusion, detecting compartment syndrome or occlusion, critical for urgent intervention to prevent tissue necrosis.
Choice C reason: Completing a neurovascular assessment evaluates pulse, color, warmth, sensation, and movement. Absent radial pulse post-fracture suggests compartment syndrome or arterial injury, risking ischemia. This confirms vascular compromise, guiding interventions like fasciotomy, addressing the pathophysiological threat to limb viability, ensuring timely treatment.
Choice D reason: Notifying the provider follows assessment. Absent radial pulse suggests compartment syndrome, where swelling impairs arterial flow. Neurovascular assessment quantifies severity (e.g., pallor, paresthesia), ensuring accurate reporting for urgent intervention, preventing delays in treating vascular compromise critical to limb preservation.
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