A client is prescribed a drug as 0.3 mcg, q4h. Calculate the dose of the medicine per day.

The flow rate of infusion is 125 mL/hr.

This answer is correct because it is based on a simple division and rounding calculation. The nurse should follow these steps to determine the flow rate of infusion:

1) Subtract the start time of the infusion from the end time of the infusion to get the duration of the infusion in hours and minutes, as follows:

15:45 - 06:57 = 8:48

Therefore, the infusion lasted for 8 hours and 48 minutes.

2) Convert the duration of the infusion to hours only by dividing the minutes by 60, since there are 60 minutes in 1 hour. Add this to the hours, as follows:

8 + (48 / 60) = 8.8

Therefore, the infusion lasted for 8.8 hours.

3) Divide the volume of the infusion by the duration of the infusion to get the flow rate in milliliters per hour, as follows:

1000 mL / 8.8 hr = 113.64 mL/hr

Therefore, the flow rate is 113.64 mL/hr.

4) Round the flow rate to the nearest whole number, as follows:

113.64 mL/hr ≈ 114 mL/hr

Therefore, the flow rate is approximately 114 mL/hr.

5) Adjust the flow rate to a standard value that can be set on an IV pump or gravity drip chamber, as follows:

114 mL/hr → 125 mL/hr

Therefore, the flow rate of infusion is 125 mL/hr.

This answer is correct because BSA is the most accurate method for calculating the child's dose from the adult dose¹². BSA takes into account the child's weight and height, and reflects the physiological function and organ growth of the child beter than weight alone¹. BSA can be calculated using a nomogram or a formula based on the child's weight and height¹. The child's dose can then be calculated by multiplying the adult dose by the ratio of the child's BSA to the average adult BSA (1.73 m2)¹. For example:

Child dose by BSA = (mg/day) = Adult Dose in mg/day x BSA in m2 / 1.73

OR

Child dose by BSA = (mg/day) = Adult Dose in mg/m2 x BSA in m2

The other options are not correct because they are not accurate methods for calculating the child's dose from the adult dose. Actual body weight and ideal body weight may not account for individual variations in pharmacokinetics, pharmacodynamics, or clinical response. Actual body height is not a reliable indicator of drug dosage, as it does not reflect the body mass or organ function of the child.