A 51-year-old woman will be taking selective estrogen receptor modulators (SERMs) as part of treatment for postmenopausal osteoporosis. The nurse reviews potential contraindications, including which condition?

Venous thromboembolism

Breast cancer

Hypocalcemia

Stress fractures

Answer and Explanation

The Correct Answer is A

Choice A reason: Venous thromboembolism is a contraindication for taking SERMs. SERMs are drugs that act like estrogen in some tissues and block estrogen in others. They can help prevent bone loss and fractures in postmenopausal women, but they can also increase the risk of blood clots in the veins, such as deep vein thrombosis and pulmonary embolism. Therefore, women who have a history of or are at high risk for venous thromboembolism should not take SERMs.

Choice B reason: Breast cancer is not a contraindication for taking SERMs. In fact, some SERMs, such as tamoxifen and raloxifene, are used to treat or prevent breast cancer in women who have estrogen receptor-positive tumors. These SERMs block the effects of estrogen in the breast tissue and reduce the growth of cancer cells.

Choice C reason: Hypocalcemia is not a contraindication for taking SERMs. Hypocalcemia is a low level of calcium in the blood. SERMs do not affect calcium levels directly, but they can help prevent calcium loss from the bones by mimicking the effects of estrogen in the bone tissue. However, women who take SERMs should also take adequate calcium and vitamin D supplements to maintain bone health.

Choice D reason: Stress fractures are not a contraindication for taking SERMs. Stress fractures are small cracks in the bones that result from repeated stress or overuse. SERMs can help prevent stress fractures by strengthening the bones and reducing the risk of osteoporosis. However, women who take SERMs should also avoid excessive or inappropriate physical activity that can cause stress fractures.

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Correct Answer is C

Explanation

Choice A reason: This is incorrect because alopecia is not a common or serious adverse effect of finasteride. However, the patient should be informed that finasteride may cause decreased hair growth or loss of hair in some cases.

Choice B reason: This is incorrect because finasteride is not given by injection, but by oral route. The patient should take one tablet daily with or without food.

Choice C reason: This is correct because finasteride can cause birth defects in male fetuses if it is absorbed through the skin or ingested by pregnant women. The patient should wear gloves when handling the tablets and avoid contact with crushed or broken tablets.

Choice D reason: This is incorrect because finasteride can be taken with or without food. However, the patient should take it at the same time each day and follow the provider's instructions.

A. Dosage B. Route C. Medication D. Time/frequency

Correct Answer is C

Explanation

Choice A reason: This is incorrect because the dosage is given in the prescription as 500 mg, which indicates the amount of the drug to be administered.

Choice B reason: This is incorrect because the route is given in the prescription as PO, which stands for per os or by mouth, which indicates how the drug is to be administered.

Choice C reason: This is correct because the medication is not given in the prescription, which is the name of the drug to be administered. The nurse should ask the provider to clarify the medication name and spell it out if necessary.

Choice D reason: This is incorrect because the time/frequency is given in the prescription as BID, which stands for bis in die or twice a day, which indicates when and how often the drug is to be administered.

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A 51-year-old woman will be taking selective estrogen receptor modulators (SERMs) as part of treatment for postmenopausal osteoporosis. The nurse reviews potential contraindications, including which condition?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

During the administration of finasteride, the nurse must remember which important precaution?

Correct Answer is C

Explanation

A nurse is receiving a telephone prescription for a client and documents it as metformin 500 mg PO BID. Which of the following elements should the nurse identify is missing from the prescription?

Correct Answer is C

Explanation

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