A 51-year-old woman will be taking selective estrogen receptor modulators (SERMs) as part of treatment for postmenopausal osteoporosis. The nurse reviews potential contraindications, including which condition?
Venous thromboembolism
Breast cancer
Hypocalcemia
Stress fractures
The Correct Answer is A
Choice A reason: Venous thromboembolism is a contraindication for taking SERMs. SERMs are drugs that act like estrogen in some tissues and block estrogen in others. They can help prevent bone loss and fractures in postmenopausal women, but they can also increase the risk of blood clots in the veins, such as deep vein thrombosis and pulmonary embolism. Therefore, women who have a history of or are at high risk for venous thromboembolism should not take SERMs.
Choice B reason: Breast cancer is not a contraindication for taking SERMs. In fact, some SERMs, such as tamoxifen and raloxifene, are used to treat or prevent breast cancer in women who have estrogen receptor-positive tumors. These SERMs block the effects of estrogen in the breast tissue and reduce the growth of cancer cells.
Choice C reason: Hypocalcemia is not a contraindication for taking SERMs. Hypocalcemia is a low level of calcium in the blood. SERMs do not affect calcium levels directly, but they can help prevent calcium loss from the bones by mimicking the effects of estrogen in the bone tissue. However, women who take SERMs should also take adequate calcium and vitamin D supplements to maintain bone health.
Choice D reason: Stress fractures are not a contraindication for taking SERMs. Stress fractures are small cracks in the bones that result from repeated stress or overuse. SERMs can help prevent stress fractures by strengthening the bones and reducing the risk of osteoporosis. However, women who take SERMs should also avoid excessive or inappropriate physical activity that can cause stress fractures.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is ["A","C"]
Explanation
Choice A reason: Tremors are a common sign of hypoglycemia, which occurs when the blood glucose level drops below 70 mg/dL. Hypoglycemia can cause shakiness, nervousness, and anxiety.
Choice B reason: Polydipsia, or excessive thirst, is not a manifestation of hypoglycemia, but rather of hyperglycemia, which occurs when the blood glucose level is too high. Hyperglycemia can cause dehydration, dry mouth, and increased urination.
Choice C reason: Confusion is another common sign of hypoglycemia, which can affect the brain's function and cognition. Hypoglycemia can cause dizziness, headache, difficulty concentrating, and impaired judgment.

Choice D reason: Polyphagia, or excessive hunger, is also not a manifestation of hypoglycemia, but rather of hyperglycemia. Hyperglycemia can cause the body to break down muscle and fat for energy, resulting in weight loss and increased appetite.
Choice E reason: Polyuria, or excessive urination, is also not a manifestation of hypoglycemia, but rather of hyperglycemia. Hyperglycemia can cause the kidneys to excrete excess glucose in the urine, leading to fluid loss and electrolyte imbalance.
Correct Answer is A
Explanation
Choice A reason: This is correct because medroxyprogesterone is available as a depot injection that is given intramuscularly every three months. This provides a long-acting and effective contraception for women who do not want to take oral pills or use other methods.
Choice B reason: This is incorrect because medroxyprogesterone is not available as a vaginal form. However, there are other contraceptive options that can be inserted vaginally, such as rings, diaphragms, or caps.
Choice C reason: This is incorrect because medroxyprogesterone is not available as a transdermal form. However, there are other contraceptive options that can be applied to the skin, such as patches.
Choice D reason: This is incorrect because medroxyprogesterone is not available as a subcutaneous form. However, there are other contraceptive options that can be injected under the skin, such as implants.
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