Why are sublingual and buccal medications rapidly absorbed?
They are metabolized in the liver.
Their action is located in the mouth.
These drugs pass directly into systemic circulation.
Blood flow is diminished in these sites.
The Correct Answer is C
Sublingual and buccal medications are rapidly absorbed because they are placed under the tongue or between the cheek and gum, where they dissolve and are absorbed directly into the bloodstream through the mucous membranes in the mouth. This allows for rapid absorption and bypasses the liver’s first-pass metabolism.
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Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
Cyclosporine is an immunosuppressant medication that is often used following organ transplant to prevent rejection. Grapefruit juice can increase the absorption of cyclosporine, leading to an increased risk of side effects and toxicity. Therefore, clients taking cyclosporine should be advised to avoid grapefruit and grapefruit juice while taking this medication. Pepperoni and smoked salmon do not have any known interactions with cyclosporine. Orange juice may also interact with cyclosporine, but not to the same extent as grapefruit juice. It is generally recommended that clients taking cyclosporine avoid drinking large amounts of orange juice and to inform their healthcare provider if they experience any adverse effects.
Correct Answer is D
Explanation
A.Sterile technique should ideally be used when handling the distal portion of the eyedropper to prevent introducing pathogens into the eye, as the eye is a sensitive area susceptible to infection.
B.When cleaning the eye, it is recommended to wipe from the inner canthus to the outer canthus to avoid bringing contaminants from the outer area closer to the tear duct, which reduces the risk of infection.
C.Applying pressure to the bridge of the nose is ineffective for preventing systemic absorption of the medication. Instead, pressure should be applied to the inner canthus (the nasolacrimal duct area) for about 1-2 minutes after instillation.
D.The correct technique for administering eye drops involves placing the prescribed number of drops into the conjunctival sac, not directly onto the cornea, as this can cause irritation and discomfort. Administering drops into the conjunctival sac allows for better absorption of the medication.
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