Which treatment approach involves delivering a continuous subcutaneous insulin infusion using an insulin pump and providing bolus doses before meals to mimic physiologic insulin secretion?
Oral antidiabetic medication therapy.
Basal-bolus insulin therapy.
Sliding-scale insulin therapy.
Insulin glargine therapy.
The Correct Answer is B
Basal-bolus insulin therapy involves administering a continuous basal insulin infusion to provide background insulin coverage and delivering bolus doses of insulin before meals to cover postprandial glucose elevations.
Incorrect choices:
a. This choice is incorrect. Oral antidiabetic medications are not used in basal-bolus insulin therapy.
c. This choice is incorrect. Sliding-scale insulin therapy involves adjusting insulin doses based on current blood glucose levels, rather than providing consistent basal and mealtime coverage.
d. This choice is incorrect. Insulin glargine therapy provides long-acting basal insulin coverage but does not involve bolus doses before meals.
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Related Questions
Correct Answer is C
Explanation
Prolonged hyperglycemia in diabetes can lead to the formation of advanced glycation end products (AGEs), which contribute to tissue damage, inflammation, and complications such as neuropathy and nephropathy.
Incorrect choices:
a. This choice is incorrect. Hypoglycemic episodes are associated with low blood sugar, not prolonged hyperglycemia.
b. This choice is incorrect. Increased cellular glucose uptake and energy production would not be consequences of prolonged hyperglycemia; rather, hyperglycemia impairs cellular glucose uptake.
d. This choice is incorrect. Prolonged hyperglycemia leads to insulin resistance, not enhanced insulin sensitivity.
Correct Answer is A
Explanation
Type 1 diabetes mellitus is an autoimmune condition in which the body's immune system attacks and destroys pancreatic beta cells, resulting in a lack of insulin production.
Incorrect choices:
b. This choice is incorrect. Type 2 diabetes mellitus is characterized by insulin resistance and impaired insulin secretion, but pancreatic beta cells are not completely destroyed.
c. This choice is incorrect. Gestational diabetes mellitus occurs during pregnancy and is not caused by autoimmune destruction of pancreatic beta cells.
d. This choice is incorrect. Prediabetes is a condition in which blood glucose levels are higher than normal but not high enough to be classified as diabetes. It is not characterized by autoimmune destruction of beta cells.
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