Which statement indicates that the nurse understands what the half-life of a drug means?
Drugs with a short half-life have a greater risk for toxicity
Half-life is not affected by renal or hepatic function
if a medication has a long half-life. dosage times can be longer intervals & the drug remains effective
Half of the effective portion of the drug is metabolized by the liver
The Correct Answer is C
C. The half-life of a drug refers to the time it takes for the concentration of the drug in the bloodstream to be reduced by half. If a medication has a long half-life, it means that it stays in the body for a longer period before being eliminated. This allows for less frequent dosing intervals while still maintaining therapeutic effectiveness.
A. Drugs with a short half-life are typically cleared from the body more quickly. While they may require more frequent dosing to maintain therapeutic levels, they do not necessarily have a greater risk for toxicity compared to drugs with longer half-lives. In fact, drugs with longer half-lives can accumulate in the body over time, potentially increasing the risk of toxicity.
B. The half-life of a drug can be significantly influenced by renal (kidney) and hepatic (liver) function. Impaired renal or hepatic function can prolong the half-life of a drug, leading to slower elimination and potentially increased risk of adverse effects.
D. This statement describes the concept of drug metabolism rather than the half-life. Drug metabolism refers to the biochemical alteration of drugs by enzymes, often occurring in the liver. The half-life, on the other hand, specifically relates to the elimination of the drug from the body.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
A. This principle emphasizes the duty to do no harm. In the case of the client undergoing chemotherapy and experiencing severe side effects that significantly reduce their quality of life, the principle of nonmaleficence comes into question. Chemotherapy, while aimed at treating cancer, often causes substantial side effects that can impact a patient's well-being
BThis principle relates to fairness and equality in the distribution of resources, treatments, and outcomes. In the context of cancer treatment, justice could be considered in terms of ensuring equitable access to chemotherapy and supportive care, regardless of socioeconomic status or other factors.
C Fidelity refers to the duty to be faithful, keep promises, and maintain trust in the patient-nurse relationship. In this context, fidelity would involve the nurse advocating for the client's best interests, including addressing their concerns about the severe side effects of chemotherapy and their impact on quality of life.
D. Autonomy refers to respecting the right of the patient to make their own decisions about their care and treatment. In the context of cancer treatment, autonomy would involve ensuring that the client has sufficient information about their condition, prognosis, treatment options, and potential side effects to make informed decisions. However, autonomy may also be challenged when severe side effects significantly impact the client's ability to maintain their desired quality of life despite ongoing treatment.
Correct Answer is D
Explanation
D. This refers to the inability to clear secretions or obstructions from the respiratory tract to maintain airway patency. Based on the client's complaint of difficulty moving mucus from the throat to the mouth for expectoration, ineffective airway clearance is the priority problem. The client's reluctance to cough and deep breathe due to pain further exacerbates this issue, as effective airway clearance is crucial for preventing complications such as respiratory infections or atelectasis post-operatively.
A. Activity intolerance refers to insufficient physiological or psychological energy to endure or complete required or desired daily activities. In the case of a one-day post-operative client experiencing difficulty clearing mucus, activity intolerance is not the priority problem. The client's main issue is related to respiratory function and airway clearance rather than overall activity tolerance.
B. This refers to abnormal respiratory rate, depth, or rhythm that does not provide adequate ventilation. While the client's complaint of difficulty moving mucus and reluctance to cough or deep breathe suggests some respiratory discomfort, the main issue appears to be the inability to effectively clear airway secretions rather than an overall ineffective breathing pattern.
C. This refers to the inability to exchange oxygen and carbon dioxide across the alveolar-capillary membranes. While mucus in the throat can potentially affect gas exchange if it obstructs airflow significantly, the client's primary complaint is about difficulty clearing mucus rather than signs and symptoms of inadequate oxygenation or ventilation.
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