Which statement indicates that the nurse understands what the half-life of a drug means?
Drugs with a short half-life have a greater risk for toxicity
Half-life is not affected by renal or hepatic function
if a medication has a long half-life. dosage times can be longer intervals & the drug remains effective
Half of the effective portion of the drug is metabolized by the liver
The Correct Answer is C
C. The half-life of a drug refers to the time it takes for the concentration of the drug in the bloodstream to be reduced by half. If a medication has a long half-life, it means that it stays in the body for a longer period before being eliminated. This allows for less frequent dosing intervals while still maintaining therapeutic effectiveness.
A. Drugs with a short half-life are typically cleared from the body more quickly. While they may require more frequent dosing to maintain therapeutic levels, they do not necessarily have a greater risk for toxicity compared to drugs with longer half-lives. In fact, drugs with longer half-lives can accumulate in the body over time, potentially increasing the risk of toxicity.
B. The half-life of a drug can be significantly influenced by renal (kidney) and hepatic (liver) function. Impaired renal or hepatic function can prolong the half-life of a drug, leading to slower elimination and potentially increased risk of adverse effects.
D. This statement describes the concept of drug metabolism rather than the half-life. Drug metabolism refers to the biochemical alteration of drugs by enzymes, often occurring in the liver. The half-life, on the other hand, specifically relates to the elimination of the drug from the body.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
B. Before, during, and after providing hygiene care, the nurse should continually assess the client's response to activity. Signs such as increased heart rate, shortness of breath, fatigue, or discomfort should be monitored closely. Assessing the client's response allows the nurse to adjust care activities as needed to prevent exacerbation of symptoms or complications.
A. Administering oxygen may be necessary if the client has respiratory compromise or if oxygen saturation levels are low during activities. However, this intervention should be based on the client's specific needs as assessed by the nurse and should not necessarily be a routine intervention
C Providing regular rest periods is an important intervention for clients with activity intolerance. However, the assessment will guide how and when these interventions should be implemented.
D. Fowler's position are also important, but the assessment will guide how and when these interventions should be implemented.
Correct Answer is ["A","E"]
Explanation
A. Venous ulcers often have irregular wound borders. This is due to the underlying venous hypertension and tissue breakdown, which can lead to irregular shapes of the ulcer.
E. Significant edema, particularly in the lower leg and ankle area (often graded as +2 or +3), is commonly associated with venous ulcers. Venous insufficiency leads to fluid accumulation in the tissues, resulting in edema.
B. This is less likely to be associated with a venous ulcer. Venous ulcers typically occur on the lower leg, particularly around the medial or lateral malleolus, rather than on the plantar aspect of the foot.
C. Severe pain, especially on a scale of 9 out of 10, is less typical of venous ulcers. Venous ulcers are usually associated with mild to moderate discomfort or pain, often described as aching or heaviness rather than severe pain.
D. Venous ulcers typically exhibit moderate to heavy serous drainage. This is due to the chronic inflammation and venous congestion that characterize venous insufficiency.
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