Which statement indicates that the nurse understands what the half-life of a drug means?
Drugs with a short half-life have a greater risk for toxicity
Half-life is not affected by renal or hepatic function
if a medication has a long half-life. dosage times can be longer intervals & the drug remains effective
Half of the effective portion of the drug is metabolized by the liver
The Correct Answer is C
C. The half-life of a drug refers to the time it takes for the concentration of the drug in the bloodstream to be reduced by half. If a medication has a long half-life, it means that it stays in the body for a longer period before being eliminated. This allows for less frequent dosing intervals while still maintaining therapeutic effectiveness.
A. Drugs with a short half-life are typically cleared from the body more quickly. While they may require more frequent dosing to maintain therapeutic levels, they do not necessarily have a greater risk for toxicity compared to drugs with longer half-lives. In fact, drugs with longer half-lives can accumulate in the body over time, potentially increasing the risk of toxicity.
B. The half-life of a drug can be significantly influenced by renal (kidney) and hepatic (liver) function. Impaired renal or hepatic function can prolong the half-life of a drug, leading to slower elimination and potentially increased risk of adverse effects.
D. This statement describes the concept of drug metabolism rather than the half-life. Drug metabolism refers to the biochemical alteration of drugs by enzymes, often occurring in the liver. The half-life, on the other hand, specifically relates to the elimination of the drug from the body.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
C. A comprehensive approach ensures that all aspects of patient care, safety, and organizational processes are thoroughly reviewed and addressed according to TJC standards. This includes comprehensive assessments of patient needs, care plans, and quality improvement initiatives.
A. This term typically refers to the process of capturing images or videos at intervals over time. In the context of healthcare and TJC requirements, "time-lapsed" is not a standard term used by TJC.
B An emergency situation refers to a sudden and often critical medical situation requiring immediate attention and intervention. While TJC does have standards related to emergency preparedness and response in healthcare facilities, "emergency" is not specifically a type of TJC requirement in the context provided.
D. A focused approach refers to concentrating on specific areas or issues within healthcare organizations to address particular concerns or improvements. However, this is not specific about TJC.
Correct Answer is A
Explanation
A. One of the primary reasons for administering IV fluids is to correct imbalances in fluid volume or electrolyte concentrations. Examples include correcting dehydration, restoring electrolyte levels (such as sodium, potassium), and addressing fluid losses due to vomiting, diarrhea, or excessive sweating.
B. IV fluids are typically used to increase intravascular volume rather than decrease it. In conditions such as hypovolemia (low blood volume), IV fluids are administered to restore blood volume and improve circulation.
C. Third spacing refers to the abnormal accumulation of fluid in interstitial spaces, which can occur in conditions like sepsis, burns, or trauma. IV fluids are not typically administered to increase third spacing; rather, treatment aims to redistribute fluids and improve fluid balance.
D. Enteral fluids are fluids administered directly into the gastrointestinal tract (via oral or tube feeding). IV fluids are administered directly into the bloodstream and are used when enteral administration is not feasible or sufficient.
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