Which of the following should be included in the teaching plan for a patient receiving glargine (Lantus), "peakless" basal insulin?
It is rapidly absorbed, has a fast onset of action
Administer the total daily dosage in two doses
Draw up the drug first, then add regular insulin
Do not mix with other insulins
The Correct Answer is D
A. It is rapidly absorbed, has a fast onset of action:
Explanation: This statement is incorrect. Glargine (Lantus) actually has a slow onset of action and a prolonged duration of action. It is formulated to provide a steady level of insulin in the body over an extended period.
B. Administer the total daily dosage in two doses:
Explanation: This is not the recommended administration for glargine. It is typically administered once daily to provide basal insulin coverage over a 24-hour period.
C. Draw up the drug first, then add regular insulin:
Explanation: Mixing glargine with other insulins is not recommended. Glargine should be administered separately to maintain its extended duration of action. It should not be mixed with other insulins in the same syringe.
D. Do not mix with other insulins:
Explanation: This is the correct statement. Glargine should not be mixed with other insulins. It should be administered alone to maintain its "peakless" basal coverage. Mixing it with other insulins could alter its pharmacokinetics and compromise its effectiveness.
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Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is ["B","C","E"]
Explanation
A. Buffalo hump:
Explanation: A buffalo hump is associated with excess cortisol, which is not a typical manifestation of Addison's disease. Instead, patients with Addison's disease may experience weight loss and muscle wasting.
B. Hyponatremia:
Explanation: Correct. Hyponatremia (low sodium levels) can occur in Addison's disease due to the loss of aldosterone, which plays a role in sodium and water balance.
C. Decreased glucose level:
Explanation: Correct. Addison's disease can lead to hypoglycemia (low blood glucose levels) because cortisol, which is important for maintaining blood glucose, is deficient.
D. Weight gain:
Explanation: Weight gain is not a typical manifestation of Addison's disease. Instead, weight loss and muscle wasting may occur.
E. Craving for salt:
Explanation: Correct. Addison's disease can lead to salt craving, as aldosterone deficiency results in increased sodium loss and potassium retention.

Correct Answer is A
Explanation
A. IV administration of 50% dextrose in water:
This is the correct answer. The client is severely hypoglycemic, and IV administration of 50% dextrose in water is the most rapid way to raise the blood glucose level in an emergency situation.
B. IV bolus of 5% dextrose in 0.45% NaCl:
While this solution contains dextrose, it is not as concentrated as 50% dextrose. In an emergency, a more concentrated solution is needed to rapidly correct severe hypoglycemia.
C. Administer 4 oz. clear juice:
Oral intake may be too slow in this critical situation. IV administration is more appropriate for rapidly raising the blood glucose level.
D. Subcutaneous administration of 12 to 15 units of regular insulin:
This would further lower the blood glucose level and is not appropriate for treating severe hypoglycemia.
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