A client with a history of Addison's disease and flu-like symptoms accompanied by nausea and vomiting over the past week is brought to the facility. His wife reports that he acted confused and was extremely weak when he awoke that morning. The client's blood pressure is 90/58 mm Hg, his pulse is 116 beats/minute, and his temperature is 101° F (38.3° C). A diagnosis of acute adrenal insufficiency is made. What should the nurse expect to administer by I.V. infusion?

Methylprednisolone (Solu-medrol)

Hypotonic saline

Potassium (K-dur)

Regular Insulin

Answer and Explanation

The Correct Answer is A

A. Methylprednisolone (Solu-medrol):
Explanation: Acute adrenal insufficiency is a life-threatening condition characterized by a sudden deficiency of adrenal hormones. In this situation, intravenous glucocorticoids such as methylprednisolone are administered to replace the deficient hormones and stabilize the patient. This is the appropriate intervention to address the acute adrenal crisis.

B. Hypotonic saline:
Explanation: Hypotonic saline is not the first-line treatment for acute adrenal insufficiency. The priority is to replace glucocorticoids to address the adrenal hormone deficiency.

C. Potassium (K-dur):
Explanation: While electrolyte imbalances can occur in adrenal insufficiency, potassium replacement alone does not address the primary issue of glucocorticoid deficiency in acute adrenal insufficiency.

D. Regular Insulin:
Explanation: Regular insulin is not the primary treatment for acute adrenal insufficiency. Glucocorticoid replacement, such as methylprednisolone, is the key intervention.

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Correct Answer is C

Explanation

A. The need to match the daily steroid dose to immediate symptoms:
Explanation: Adjusting the steroid dose based on immediate symptoms is not a recommended approach. Patients should follow the prescribed regimen provided by their healthcare provider.

B. The importance of monitoring liver function:
Explanation: While monitoring liver function is important for some medications, it is not the primary focus when teaching about hormone replacement therapy in Addison's disease. The emphasis is on the need for life-long steroid replacement.

C. The need for life-long steroid replacement:
Explanation: Patients with Addison's disease require life-long steroid replacement therapy to compensate for the deficiency in adrenal hormones. It's important for the patient to understand that adherence to the prescribed steroid regimen is essential for maintaining health and preventing adrenal crisis.

D. The possibility extreme weight loss from the use of corticosteroids:
Explanation: While corticosteroids can have various side effects, extreme weight loss is not a typical or desired outcome of steroid therapy for Addison's disease. Weight changes and potential side effects should be discussed, but the emphasis should be on the importance of long-term steroid replacement.

A. It is rapidly absorbed, has a fast onset of action B. Administer the total daily dosage in two doses C. Draw up the drug first, then add regular insulin D. Do not mix with other insulins

Correct Answer is D

Explanation

A. It is rapidly absorbed, has a fast onset of action:
Explanation: This statement is incorrect. Glargine (Lantus) actually has a slow onset of action and a prolonged duration of action. It is formulated to provide a steady level of insulin in the body over an extended period.

B. Administer the total daily dosage in two doses:
Explanation: This is not the recommended administration for glargine. It is typically administered once daily to provide basal insulin coverage over a 24-hour period.

C. Draw up the drug first, then add regular insulin:
Explanation: Mixing glargine with other insulins is not recommended. Glargine should be administered separately to maintain its extended duration of action. It should not be mixed with other insulins in the same syringe.

D. Do not mix with other insulins:
Explanation: This is the correct statement. Glargine should not be mixed with other insulins. It should be administered alone to maintain its "peakless" basal coverage. Mixing it with other insulins could alter its pharmacokinetics and compromise its effectiveness.

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Naxlex Comprehensive Predictor Exams

The nurse is caring for a patient with Addison's disease who is scheduled for discharge. When teaching the patient about hormone replacement therapy, the nurse should address what topic?

Correct Answer is C

Explanation

Which of the following should be included in the teaching plan for a patient receiving glargine (Lantus), "peakless" basal insulin?

Correct Answer is D

Explanation

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