Which of the following phases of pharmacokinetics is described as the removal of the drug or its metabolites through the kidneys, gastrointestinal tract, skin, or lungs?

Distribution

Metabolism

Absorption

Excretion

Answer and Explanation

The Correct Answer is D

A.   Distribution: This phase involves the transportation of the drug throughout the body after absorption, not removal.
B.   Metabolism: This phase involves the chemical alteration of the drug in the body, often in the liver, not its removal.
C.   Absorption: This phase involves the drug entering the bloodstream after administration.
D.   Excretion: This is the phase where the drug or its metabolites are removed from the body through various routes such as the kidneys, gastrointestinal tract, skin, or lungs.

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Correct Answer is D

Explanation

A. Loperamide (Imodium): This is an anti-diarrheal medication and does not protect mucosal ulcers.
B. Cimetidine (Tagamet HB): Cimetidine is an H2 blocker used to reduce stomach acid, but it does not form a protective barrier like sucralfate.
C. Docusate sodium (Colace): This is a stool softener and is not used for protecting gastric ulcers.
D. Sucralfate (Carafate): Sucralfate is a mucosal protectant that binds to the ulcer and creates a protective barrier, preventing further injury from stomach acid and pepsin.

A. Prolonged QT interval B. Spasms of the neck and face C. Nausea D. Vomiting

Correct Answer is A

Explanation

A. Ondansetron (Zofran) can cause a prolonged QT interval, which may lead to arrhythmias. This is a known side effect and should be monitored.
B. Spasms of the neck and face are more likely to occur with medications that have extrapyramidal side effects, such as certain antipsychotics, not ondansetron.
C. Nausea and D. Vomiting are the symptoms ondansetron is intended to treat, so these are not complications.

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Which of the following phases of pharmacokinetics is described as the removal of the drug or its metabolites through the kidneys, gastrointestinal tract, skin, or lungs?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

The nurse is providing an in-service on mucosal protectants. What medication protects the ulcer from further injury from acid and pepsin and is a viscous substance that can stick to the ulcer for up to 6 hours?

Correct Answer is D

Explanation

A nurse administered ondansetron (Zofran) IV to a client 30 minutes ago. Which of the following findings should the nurse recognize as a complication of this medication?

Correct Answer is A

Explanation

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