Which of the following phases of pharmacokinetics is described as the removal of the drug or its metabolites through the kidneys, gastrointestinal tract, skin, or lungs?

Distribution

Metabolism

Absorption

Excretion

Answer and Explanation

The Correct Answer is D

A.   Distribution: This phase involves the transportation of the drug throughout the body after absorption, not removal.
B.   Metabolism: This phase involves the chemical alteration of the drug in the body, often in the liver, not its removal.
C.   Absorption: This phase involves the drug entering the bloodstream after administration.
D.   Excretion: This is the phase where the drug or its metabolites are removed from the body through various routes such as the kidneys, gastrointestinal tract, skin, or lungs.

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Correct Answer is A

Explanation

A. Respiratory depression is a hallmark sign of opioid toxicity. A rate of 7 breaths per minute indicates severe respiratory depression, which can be life-threatening and requires immediate intervention with naloxone.
B. Anxiety is not typically associated with opioid toxicity, but rather may be a sign of withdrawal or other conditions.
C. Fever is not a sign of opioid toxicity. It may be a sign of infection or other medical issues.
D. Hypertension is not typical of opioid toxicity; opioids usually cause hypotension, not hypertension.

A. Take this medication with mess. B. Take this medication with an antacid if heartburn occurs C. Take this medication in the morning before eating. D. Chew the tablets to increase bioavailability.

Correct Answer is C

Explanation

A. Alendronate should be taken on an empty stomach with a full glass of water, at least 30 minutes before any food or other medications. This ensures better absorption.
B. Alendronate should not be taken with antacids, as they can interfere with its absorption. The patient should not lie down immediately after taking it to prevent esophageal irritation.
C. This is the correct recommendation. Alendronate should be taken in the morning, on an empty stomach, with a full glass of water. The patient should then remain upright for at least 30 minutes.
D. Alendronate tablets should be swallowed whole. Crushing or chewing the tablet may increase the risk of esophageal irritation and reduce its effectiveness.

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Which of the following phases of pharmacokinetics is described as the removal of the drug or its metabolites through the kidneys, gastrointestinal tract, skin, or lungs?

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Naxlex Comprehensive Predictor Exams

The nurse is caring for a client who received a high amount of fentanyl three hours ago. The nurse understands that she should anticipate a prescription for naloxone (Narcan). Which of the following signs is suggestive of opioid toxicity triad?

Correct Answer is A

Explanation

A nurse is teaching a client who has osteoporosis and a new prescription for alendronate (Fosamax). Which of the following instructions should the nurse provide?

Correct Answer is C

Explanation

A nurse is preparing to administer furosemide (Lasix) to a client. Which of the following findings should the nurse hold the medication and notify the provider? (Select All That Apply.).

A nurse is teaching diabetic clients about the use of insulin. For which of the following types of insulin should the nurse tell the clients to expect an onset of 15 to 30 minutes?

A client has been newly prescribed with cyclobenzaprine (Flexeril). Which of the following statements indicates the correct therapeutic use for this medication?

The nurse is educating a client about taking a tetracycline along with an antacid. The nurse explains to the client not to take these two medications because the antacid can reduce the absorption of the tetracycline. When one drug reduces the effect of another, it is:

The nurse is providing an in-service on non-steroidal anti-inflammatory drugs (NSAIDs). Which of the following medications is a first-generation NSAID that inhibits both COX-1 and COX-2 enzymes?

A nurse is educating a client about a new prescription for morphine sulfate (Astramorph). Which of the following statement should the nurse include in the teaching about morphine?

A nurse is caring for a client who is prescribed with cimetidine (Tagamet HB). The nurse understands that complications of cimetidine (Tagamel HB) include: (Select All That Apply.).

A nurse is reviewing the phases of pharmacokinetics. Which of the following phases is the change of a drug into a less or more potent or more soluble form after it passes through the liver?