Which of the following factors contributes to the development of osteoarthritis?
Chronic inflammation of the synovial membrane
Hyperactivity of the immune system
Deficiency of collagen in joint cartilage
Excessive physical activity and joint overuse
The Correct Answer is D
Excessive physical activity and joint overuse can contribute to the development of osteoarthritis. Repetitive use and mechanical stress on the joints can lead to cartilage degeneration over time.
a. Osteoarthritis is primarily a non-inflammatory condition. Chronic inflammation of the synovial membrane is more characteristic of other types of arthritis, such as rheumatoid arthritis.
b. Osteoarthritis is not related to hyperactivity of the immune system. It is not an autoimmune disease, and the immune system is not involved in its pathogenesis.
c. Collagen is an essential component of joint cartilage. A deficiency of collagen would weaken the cartilage and contribute to joint degeneration. However, osteoarthritis is not primarily caused by collagen deficiency.
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Related Questions
Correct Answer is B
Explanation
Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) commonly prescribed for the initial management of osteoarthritis. It helps reduce pain and inflammation in the affected joints. Methotrexate, prednisone, and infliximab are medications used to manage inflammatory arthritis conditions, such as rheumatoid arthritis, and are not typically prescribed for osteoarthritis.
a. Methotrexate is used in the management of inflammatory arthritis conditions, such as rheumatoid arthritis, and is not typically prescribed for osteoarthritis.
c. Prednisone is a corticosteroid used to manage inflammatory arthritis conditions, such as rheumatoid arthritis, and is not typically prescribed for osteoarthritis.
d. Infliximab is a biologic medication used in the management of inflammatory arthritis conditions, such as rheumatoid arthritis, and is not typically prescribed for osteoarthritis.
Correct Answer is D
Explanation
Obesity is a significant risk factor for the development of osteoarthritis, especially in weight-bearing joints such as knees and hips. Excess body weight increases stress on the joints, leading to cartilage damage and joint degeneration.
a. Regular physical activity is generally beneficial for joint health and may help prevent osteoarthritis.
b. Young age is not a risk factor for osteoarthritis; it is more common in older adults.
c. Family history of osteoporosis is not directly linked to osteoarthritis; however, a family history of osteoarthritis itself may increase the risk.
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