Which of the following statements best describes the introduction of osteoarthritis?
Osteoarthritis is a systemic autoimmune disease that affects multiple joints in the body.
Osteoarthritis is a condition that primarily affects young adults and is characterized by joint inflammation.
Osteoarthritis is a degenerative joint disease that primarily involves the breakdown of joint cartilage.
Osteoarthritis is caused by the deposition of urate crystals in the joints, leading to joint pain and stiffness.
The Correct Answer is C
Osteoarthritis is a degenerative joint disease characterized by the gradual breakdown of joint cartilage over time. It is not an autoimmune disease, and it does not involve inflammation like rheumatoid arthritis. While it can affect people of all ages, it is more commonly seen in older adults.
a. Osteoarthritis is not a systemic autoimmune disease. It is primarily a non-inflammatory condition, and the immune system is not involved in its pathogenesis.
b. Osteoarthritis is not a condition that primarily affects young adults. While it can occur at any age, it is more commonly seen in older individuals.
d. Osteoarthritis is not caused by the deposition of urate crystals. Urate crystal deposition is associated with gout, a different form of arthritis.
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Correct Answer is C
Explanation
Pain that worsens with weight-bearing activities and improves with rest is a classic clinical manifestation of osteoarthritis. Activity-related pain is due to the increased stress on the affected joint during movement, while rest allows for decreased pressure and relief of pain.
a. Nocturnal joint pain is more typical of inflammatory arthritis conditions like rheumatoid arthritis, not osteoarthritis.
b. Morning joint stiffness lasting for 1 hour is characteristic of inflammatory arthritis conditions like rheumatoid arthritis, not osteoarthritis.
d. Joint pain that is constant throughout the day may be seen in various joint disorders, but the pattern of pain relief with activity is more indicative of osteoarthritis.
Correct Answer is C
Explanation
The presence of Heberden's nodes, which are bony enlargements at the distal interphalangeal (DIP) joints, is a characteristic clinical manifestation of osteoarthritis. These nodes are a result of cartilage degeneration in the affected joints.
a. Joint pain that worsens with rest is more indicative of inflammatory arthritis conditions like rheumatoid arthritis, not osteoarthritis.
b. Joint pain that improves with activity is not typical of osteoarthritis, which tends to worsen with weight-bearing activities.
d. Warm and erythematous joints are signs of inflammation and are more commonly seen in inflammatory arthritis conditions, not osteoarthritis.
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