Which of the following are causes of intrarenal acute kidney injury? (Select all that apply.)

Choice A rationale
Liver cirrhosis is the most common cause of esophageal varices and portal hypertension. Cirrhosis leads to scarring of the liver, which impedes blood flow through the portal vein, causing increased pressure (portal hypertension) and the development of collateral blood vessels (varices) as the body attempts to bypass the blockage.

Choice B rationale
Throat lacerations are not related to the development of esophageal varices or portal hypertension. They are typically acute injuries and do not cause the chronic changes seen in the vasculature associated with these conditions.

Choice C rationale
Kyphosis, a curvature of the spine, does not cause esophageal varices or portal hypertension. It is a structural skeletal condition and does not affect the vasculature of the esophagus or the portal venous system.

Choice D rationale
While squamous cell cancer can occur in the esophagus, it is not a typical cause of portal hypertension or esophageal varices. These varices are usually a result of increased pressure in the portal vein, not directly from a malignancy.

Choice A reason: A new ileal conduit is a permanent life change that requires the client to learn complex self-care skills. The uncertainty regarding stoma management, fear of appliance leakage in public, and the lifestyle adjustments required often lead to significant anxiety. The nurse must address these psychological stressors during the initial postoperative period to promote successful adaptation.

Choice B reason: The continuous drainage of urine from the stoma creates a high risk for peristomal skin breakdown. Urine is caustic to the skin, and moisture trapped under the skin barrier can lead to maceration, dermatitis, or fungal infections. Maintaining a secure, well-fitted appliance and assessing the skin frequently are essential nursing interventions for this risk.

Choice C reason: Surgical creation of an ileal conduit involves bowel resection and ureteral implantation, increasing the risk for peritonitis or wound infection. Furthermore, since the conduit is a direct pathway to the kidneys without a sphincter, the client is at lifelong risk for ascending urinary tract infections or pyelonephritis requiring vigilant monitoring.

Choice D reason: While postoperative patients require fluid monitoring, an ileal conduit does not typically cause a chronic fluid volume deficit. Unlike an ileostomy, where significant water and electrolytes are lost through liquid stool, the ileal conduit simply transports urine. Unless there is excessive surgical bleeding or unrelated dehydration, this is not a primary risk.

Choice E reason: The permanent diversion of urine to an external pouch on the abdomen significantly alters the client's physical appearance and "normal" elimination process. Concerns regarding sexual function, clothing choices, and the presence of a stoma frequently lead to a disturbed body image, necessitating supportive counseling and referral to an ostomy nurse.