Which of the following are causes of intrarenal acute kidney injury? (Select all that apply.)
Hemoglobin from hemolyzed RBCs
Benign prostatic hyperplasia
Prostate cancer
Myoglobin release from necrotic muscle cells
Nephrotoxins
Correct Answer : A,D,E
Choice A rationale
Hemoglobin released from hemolyzed red blood cells (RBCs) can cause intrarenal acute kidney injury by obstructing the renal tubules and damaging the nephrons.
Choice B rationale
Benign prostatic hyperplasia is a cause of postrenal, not intrarenal, acute kidney injury as it can obstruct the flow of urine out of the bladder.
Choice C rationale
Prostate cancer, similar to benign prostatic hyperplasia, typically leads to postrenal acute kidney injury due to urinary obstruction.
Choice D rationale
Myoglobin released from necrotic muscle cells, as seen in conditions like rhabdomyolysis, can cause intrarenal acute kidney injury by precipitating in the renal tubules.
Choice E rationale
Nephrotoxins, such as certain medications, chemicals, or toxins, can directly damage the kidney tissue, leading to intrarenal acute kidney injury.
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Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is ["A","C","D","F"]
Explanation
Choice A rationale
Chocolate is known to have moderate levels of potassium and should be limited in a diet for chronic kidney disease to prevent hyperkalemia¹.
Choice B rationale
Green beans are considered a lower potassium vegetable and can be included in a kidney-friendly diet in appropriate portions².
Choice C rationale
Tomatoes are high in potassium and should be avoided by individuals with chronic kidney disease to maintain safe potassium levels¹.
Choice D rationale
Bananas are very high in potassium and are one of the most well-known foods that individuals with chronic kidney disease are advised to avoid¹.
Choice E rationale
Asparagus is lower in potassium compared to other vegetables and can be consumed in moderation by people with chronic kidney disease².
Choice F rationale
Salt substitutes often contain potassium chloride and should be avoided as they can significantly increase potassium intake, which is harmful for those with chronic kidney disease¹.
Correct Answer is ["A","B","D"]
Explanation
Choice A rationale
Smoking is a well-established risk factor for colorectal cancer. The carcinogens in tobacco smoke can lead to the formation of cancerous cells in the colon and rectum.
Choice B rationale
Obesity increases the risk of colorectal cancer, possibly due to chronic low-level inflammation associated with excess body fat, which can contribute to cancer development.
Choice C rationale
Limiting alcohol intake to less than four drinks per week is actually a protective measure against colorectal cancer, not a risk factor.
Choice D rationale
A high intake of red meat, particularly more than seven servings per week, has been linked to an increased risk of colorectal cancer due to compounds formed during digestion that can damage the lining of the colon and rectum.
Choice E rationale
A diet high in fruits, vegetables, and grains is generally considered protective against colorectal cancer due to the fiber and nutrients they provide, not a risk factor.
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