Which of the following antiviral medications prevents viral fusion with host cell membrane?
Maraviroc
Abacavir
Darunavir
Fosamprenavir.
The Correct Answer is A
Maraviroc is a CCR5 coreceptor antagonist that blocks the receptor site the HIV virus needs to interact with in order to enter the cell. It prevents viral fusion with host cell membrane by binding to the CCR5 receptor on CD4+ T cells and macrophages.
Choice B is wrong because Abacavir is wrong because it is a nucleoside reverse transcriptase inhibitor (NRTI) that inhibits the enzyme reverse transcriptase, which converts viral RNA into DNA.
It does not prevent viral fusion with host cell membrane.
Choice C is wrong because Darunavir is wrong because it is a protease inhibitor (PI) that inhibits the enzyme protease, which cleaves viral proteins into functional units.
It does not prevent viral fusion with host cell membrane.
Choice D is wrong because Fosamprenavir is wrong because it is also a protease inhibitor (PI) that inhibits the enzyme protease.
It does not prevent viral fusion with host cell membrane.
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Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
Maraviroc is aCCR5 coreceptor antagonistthat blocks the receptor site the HIV virus needs to interact with in order to enter the cell.It prevents viral fusion with host cell membrane by binding to the CCR5 receptor on CD4+ T cells and macrophages.
Choice B is wrong becauseAbacavir is wrong because it is anucleoside reverse transcriptase inhibitor (NRTI)that inhibits the enzyme reverse transcriptase, which converts viral RNA into DNA.
It does not prevent viral fusion with host cell membrane.
Choice C is wrong becauseDarunavir is wrong because it is aprotease inhibitor (PI)that inhibits the enzyme protease, which cleaves viral proteins into functional units.
It does not prevent viral fusion with host cell membrane.
Choice D is wrong becauseFosamprenavir is wrong because it is also aprotease inhibitor (PI)that inhibits the enzyme protease.
It does not prevent viral fusion with host cell membrane.
Correct Answer is C
Explanation
The client should avoid sexual intercourse until treatment is completed.This is because trichomoniasis is a sexually transmitted infection that can be passed between partners during penile-vaginal sex or through transmission of infected vaginal fluids or fomites among women who have sex with women. Therefore, abstaining from sex until both partners are cured can prevent reinfection and transmission.
Choice A is wrong because taking the medication with an antacid can reduce its absorption and effectiveness.Tinidazole should be taken with food to minimize gastrointestinal side effects.
Choice B is wrong because drinking plenty of fluids to prevent crystalluria is not relevant for tinidazole.
Crystalluria is a condition where crystals form in the urine, which can cause kidney stones or damage.This is a potential complication of some antibiotics, such as sulfonamides, but not tinidazole.
Choice D is wrong because chewing the tablets thoroughly before swallowing is not necessary for tinidazole.Tinidazole tablets are film-coated and can be swallowed whole with water.
Chewing the tablets may alter their release and absorption, and may also cause a bitter aftertaste.
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