Which statement is true regarding antimicrobial stewardship?
Antibiotic guidelines in critical care reduce the hospital length of stay.
Inappropriate antibiotic use leads to the emergence of resistance.
Antibiotic dosing has little effect on antimicrobial resistance.
An antibiotic stewardship programme leads to an increase in antimicrobial resistance.
The Correct Answer is B
Inappropriate antibiotic use leads to the emergence of resistance. This is a well-established fact that is supported by the CDC and other organizations. Resistance can occur when antibiotics are used unnecessarily, excessively, or incorrectly, and can lead to infections that are harder to treat and more costly.
Choice A is wrong because antibiotic guidelines in critical care do not necessarily reduce the hospital length of stay. Although some studies have suggested that adherence to pneumonia guidelines may improve outcomes in severe pneumonia, other studies have found no significant effect of antibiotic stewardship on hospital length of stay or mortality in critically ill patients.
Therefore, this statement is not universally true.
Choice C is wrong because antibiotic dosing has a significant effect on antimicrobial resistance. Optimal dosing of antibiotics can help eradicate infections, prevent relapse, and minimize the selection of resistant bacteria. Conversely, suboptimal dosing can lead to treatment failure, prolonged infection, and increased resistance.
Therefore, antibiotic dosing should be carefully adjusted according to the pharmacokinetic and pharmacodynamic properties of the drug and the patient.
Choice D is wrong because an antibiotic stewardship programme leads to a decrease in antimicrobial resistance, not an increase. An antibiotic stewardship programme is a coordinated effort to improve and measure the appropriate use of antibiotics by promoting the selection of the optimal drug regimen, dose, duration, and route of administration. Such programmes have been shown to reduce antibiotic consumption, resistance rates, adverse events, and costs in various settings.
Therefore, this statement is false.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
This is because nystatin suspension is an antifungal medication that works by coating the oral mucosa and killing the candida organisms.Swishing and swallowing the medication ensures that it reaches all the affected areas in the mouth and throat.
Choice B is wrong because administering the medication with a dropper to avoid aspiration is not necessary for a client who has oral candidiasis.
The client should be able to swish and swallow the medication without difficulty.
Choice C is wrong because diluting the medication with water before giving it to the client reduces its effectiveness and concentration.
The medication should be given undiluted for optimal results.
Choice D is wrong because giving the medication after meals to increase its effectiveness is not accurate.The medication should be given at least 30 minutes before or after meals to avoid interference with food or beverages.
Correct Answer is B
Explanation
This is because antibiotics act synergistically with the immune system to subdue infection, and it is critical for success that the host defenses are adequate.
Choice A is wrong becauseAge is wrong because age is a general factor that must be considered when choosing any medication, not just antimicrobials.
Choice C is wrong becauseGenetic heritage is wrong because genetic heritage is also a general factor that may affect the metabolism and excretion of medications, not the selection of antimicrobials.
Choice D is wrong becausePrevious medication reactions is wrong because previous medication reactions are also a general factor that may indicate allergies or intolerances to certain medications, not the selection of antimicrobials.
Normal ranges for immune function vary depending on the type and level of immunity measured, such as innate, adaptive, humoral or cellular immunity.Some common tests for immune function include complete blood count (CBC), immunoglobulin levels, complement levels, antibody titers and skin tests.
Normal ranges for these tests depend on the laboratory and the method used, but some examples are:
• CBC: white blood cell count 4.5-11 x 10^9/L; neutrophils 40-75%; lymphocytes 20-50%; monocytes 2-10%; eosinophils 1-6%; basophils 0-2%.
• Immunoglobulin levels: IgG 7-16 g/L; IgA 0.7-4 g/L; IgM 0.4-2.3 g/L; IgE 0-0.4 g/L.
• Complement levels: C3 0.9-1.8 g
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