A nurse is educating a group of travelers who are going to a region where malaria is endemic.
Which of the following antimalarial drugs should the nurse recommend for prophylaxis? (Select all that apply.).
Quinine
Primaquine
Mefloquine
Pyrimethamine-sulfadiazine
Atovaquone-proguanil.
Correct Answer : C,D,E
These are the antimalarial drugs that are recommended for prophylaxis by the CDC and other sources.
They are effective against the malaria parasites that are resistant to chloroquine and primaquine, which are the other two options.
Choice A is wrong because chloroquine is not effective in areas where chloroquine resistance is present, which is most of the malaria-endemic regions.
Choice B is wrong because primaquine is not used for prophylaxis, but for radical cure of vivax and ovale malaria. It also requires a test for glucose-6-phosphate dehydrogenase (G6PD) deficiency before use, as it can cause hemolysis in people with this condition.
Choice C is correct because mefloquine is a suppressive prophylactic that can be used in areas with chloroquine resistance.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
Azithromycin is a macrolide antibiotic that can cause a rare but serious side effect calledQT prolongation, which affects the electrical activity of the heart and can lead toirregular heartbeats, chest pain, and sudden cardiac death. The patient should report any signs of chest pain or palpitations to the doctor immediately.
Choice A is wrong because diarrhea is a common side effect of azithromycin that usually does not require medical attention unless it is severe or bloody.
Choice B is wrong because headache is also a common side effect of azithromycin that usually does not require medical attention unless it is severe or persistent.
Choice D is wrong because nausea is another common side effect of azithromycin that usually does not require medical attention unless it is severe or accompanied by vomiting.
Correct Answer is ["A","D"]
Explanation
Tetracycline can causephotosensitivity, which means increased sensitivity to sunlight and risk of sunburn.It can also causesuperinfection, which means overgrowth of resistant bacteria or fungi in the mouth, intestines, or vagina.
Choice B is wrong because tetracycline can causetooth discolorationin children under 8 years old, not in adults.
Choice C is wrong because tetracycline can causehepatic impairmentonly in patients with preexisting liver disease or who take high doses for a long time.
Choice E is wrong because tetracycline can causebone marrow suppressiononly in patients with preexisting blood disorders or who take high doses for a long time.
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