Which drug groups do not inhibit clot formation? (SELECT ALL THAT APPLY)

A) Bradycardia
Bradycardia (a slow heart rate) is not the most common response to nitroglycerin (NTG). While NTG can affect heart rate in some individuals, its primary action is related to blood vessels, and it typically leads to vasodilation, which more commonly results in reflex tachycardia (an increased heart rate), rather than bradycardia.

B) Tachycardia
Tachycardia (an increased heart rate) can occur as a compensatory mechanism when nitroglycerin causes vasodilation and a decrease in blood pressure. However, this is more of a secondary effect. The primary action of nitroglycerin is to lower blood pressure (by dilating blood vessels), and in response to the lowered blood pressure, the body may try to compensate by increasing the heart rate.

C) Hypotension
The most common and primary response to nitroglycerin (NTG) administration is hypotension. Nitroglycerin works by relaxing smooth muscle in blood vessels, leading to vasodilation (widening of blood vessels). This reduces the amount of work the heart has to do and lowers the overall blood pressure. Hypotension is expected as part of the therapeutic effect of NTG, especially with a larger dose or rapid administration (e.g., sublingual NTG).

D) Dry mouth
While many medications can cause dry mouth (especially anticholinergic drugs), nitroglycerin is not typically associated with this issue. Its primary action is vasodilation, and while it can cause other symptoms like headaches, dizziness, and hypotension, dry mouth is not considered a common or significant effect.

A) Social Media:
Social media is not a reliable source for evaluating medication information. Although patients may share their experiences, the information on social media can be anecdotal, unverified, and often lacks scientific evidence. Medical professionals should avoid using social media as a reference for clinical decision-making and instead rely on trusted, evidence-based resources.

B) Wikipedia:
While Wikipedia may offer general overviews of various medications, it is a crowdsourced platform and not a peer-reviewed or professional resource. The information on Wikipedia can be edited by anyone, which raises concerns about accuracy and reliability. While useful for a quick overview, it is not recommended for in-depth medication information or clinical decision-making.

C) Physicians' Desk Reference (PDR):
The Physicians' Desk Reference (PDR) is a well-established, reliable resource for medication information. It includes detailed drug monographs, including indications, dosing, contraindications, adverse effects, and drug interactions. Although it is often considered more of a reference for healthcare providers, it is a trusted and authoritative source for accurate medication information.

D) Lexicomp:
Lexicomp is an evidence-based, reputable resource that provides comprehensive drug information, including dosage recommendations, side effects, interactions, and clinical guidelines. It is frequently used by healthcare providers for decision-making in clinical practice and is considered highly reliable.

E) Micromedex:
Micromedex is another reliable, evidence-based drug information database widely used in healthcare settings. It provides drug monographs, information on drug interactions, adverse effects, and clinical recommendations, making it an essential tool for clinical decision-making.

F) American Hospital Formulary Service (AHFS) Drug Information:
The American Hospital Formulary Service (AHFS) is a trusted source of drug information that is used by healthcare providers to obtain reliable, evidence-based data. It includes detailed monographs on prescription drugs, over-the-counter medications, and other therapeutic agents, which are useful for clinicians when assessing treatment options.