Where do enteric coated tablets typically disintegrate in the body?
Esophagus
Duodenum
Stomach
Colon
The Correct Answer is B
A) Esophagus
Enteric-coated tablets are designed to not dissolve or disintegrate in the esophagus. They are coated with a protective layer that prevents the tablet from breaking down in the acidic environment of the stomach. This is to ensure that the medication is released in the part of the digestive tract where it is most needed, typically beyond the stomach.
B) Duodenum
Enteric-coated tablets are designed to disintegrate in the duodenum, which is the first part of the small intestine. The coating protects the tablet from stomach acid, allowing it to pass intact through the stomach and into the small intestine, where the pH is higher and the coating dissolves, releasing the medication for absorption.
C) Stomach
Enteric-coated tablets are specifically designed not to disintegrate in the stomach because the stomach's acidic environment could either damage the drug or cause premature release. The coating ensures that the drug is protected until it reaches the more neutral pH of the duodenum.
D) Colon
The colon is too far along in the digestive tract for enteric-coated tablets to typically disintegrate. The design of enteric coatings is intended to protect the drug until it reaches the duodenum, where absorption is most efficient. Enteric coatings are not meant to disintegrate in the colon.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
To calculate:
1. Convert units:
1 oz = 30 mL
3 oz formula = 3 oz x 30 mL/oz = 90 mL
2 oz juice = 2 oz x 30 mL/oz = 60 mL
2. Calculate total oral intake:
Total oral intake = 10 mL (medication) + 90 mL (formula) + 60 mL (juice) = 160 mL
3. Calculate IV fluid intake:
IV fluid intake = 20 mL/hr x 8 hr = 160 mL
4. Calculate total fluid intake:
Total fluid intake = 160 mL (oral) + 160 mL (IV) = 320 mL
Answer: 320 mL
Correct Answer is D
Explanation
A) Gamma globulin
Gamma globulin is a blood product used to provide passive immunity by supplying antibodies to prevent or treat certain infections. It is not used for digitalis toxicity, so A is incorrect.
B) Cardizem
Cardizem (diltiazem) is a calcium channel blocker primarily used for controlling heart rate and treating conditions such as atrial fibrillation or angina. It is not used as an antidote for digoxin toxicity, so B is incorrect.
C) Protamine
Protamine is a medication used to reverse the effects of heparin, an anticoagulant. It works by neutralizing the anticoagulant activity of heparin, but it is not used to treat digitalis (digoxin) toxicity, so C is incorrect.
D) Digoxin immune fab
Digoxin immune fab is the specific antidote for digoxin toxicity. It consists of antibodies that bind to digoxin molecules, thereby neutralizing their toxic effects on the heart. This antidote is used when a patient exhibits severe symptoms of digoxin toxicity, such as arrhythmias or life-threatening effects on the heart. Therefore, D is the correct answer.
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