Where do enteric coated tablets typically disintegrate in the body?
Esophagus
Duodenum
Stomach
Colon
The Correct Answer is B
A) Esophagus
Enteric-coated tablets are designed to not dissolve or disintegrate in the esophagus. They are coated with a protective layer that prevents the tablet from breaking down in the acidic environment of the stomach. This is to ensure that the medication is released in the part of the digestive tract where it is most needed, typically beyond the stomach.
B) Duodenum
Enteric-coated tablets are designed to disintegrate in the duodenum, which is the first part of the small intestine. The coating protects the tablet from stomach acid, allowing it to pass intact through the stomach and into the small intestine, where the pH is higher and the coating dissolves, releasing the medication for absorption.
C) Stomach
Enteric-coated tablets are specifically designed not to disintegrate in the stomach because the stomach's acidic environment could either damage the drug or cause premature release. The coating ensures that the drug is protected until it reaches the more neutral pH of the duodenum.
D) Colon
The colon is too far along in the digestive tract for enteric-coated tablets to typically disintegrate. The design of enteric coatings is intended to protect the drug until it reaches the duodenum, where absorption is most efficient. Enteric coatings are not meant to disintegrate in the colon.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
Given:
Ordered dose of Dopamine: 3 mcg/kg/min
Child's weight: 41.8 lbs
Concentration of Dopamine: 400 mg in 250 mL D5W
Step 1: Convert child's weight from pounds to kilograms:
1 pound (lb) = 0.453592 kilograms (kg)
Child's weight in kg = 41.8 lbs x 0.453592 kg/lb = 18.935 kg
Step 2: Calculate the total dose of Dopamine in mcg/min:
Total dose (mcg/min) = Ordered dose (mcg/kg/min) x Child's weight (kg)
Total dose (mcg/min) = 3 mcg/kg/min x 18.935 kg
Total dose (mcg/min) = 56.805 mcg/min
Step 3: Convert mcg to mg:
Total dose (mg/min) = Total dose (mcg/min) / 1000 mcg/mg
Total dose (mg/min) = 56.805 mcg/min / 1000 mcg/mg
Total dose (mg/min) = 0.056805 mg/min
Step 4: Calculate the total dose in mg/hr:
Total dose (mg/hr) = Total dose (mg/min) x 60 min/hr
Total dose (mg/hr) = 0.056805 mg/min x 60 min/hr
Total dose (mg/hr) = 3.4083 mg/hr
Step 5: Calculate the infusion rate in mL/hr:
Infusion rate (mL/hr) = Total dose (mg/hr) / Concentration (mg/mL)
Infusion rate (mL/hr) = 3.4083 mg/hr / (400 mg/250 mL)
Infusion rate (mL/hr) = 3.4083 mg/hr x (250 mL/400 mg)
Infusion rate (mL/hr) = 2.1301875 mL/hr
Step 6: Round to the nearest tenth:
Infusion rate (mL/hr) ≈ 2.1 mL/hr
Correct Answer is C
Explanation
A) Yes. Antacids can help alleviate heartburn caused by digoxin.
While antacids can help relieve heartburn, they do not directly alleviate heartburn caused by digoxin. In fact, antacids can interact with digoxin in a way that affects its absorption, potentially leading to suboptimal therapeutic effects.
B) Yes, you can take antacids with digoxin without any interactions.
Antacids can interact with digoxin and reduce its absorption, particularly those that contain aluminum, magnesium, or calcium. Therefore, it is important to space the administration of these medications to avoid potential drug interactions.
C) Yes, but make sure to take the antacid at least 2 hours before or after taking digoxin.. Antacids, especially those containing aluminum, calcium, or magnesium, can decrease the absorption of digoxin, reducing its effectiveness. To prevent this interaction, the nurse should advise the client to take the antacid at least 2 hours before or after taking digoxin to ensure that digoxin is properly absorbed and remains effective.
D) No, antacids can decrease the absorption of digoxin and result in a decreased drug effect.
While this statement is partly true in that antacids can decrease digoxin absorption, it is too absolute to recommend avoiding antacids altogether. The key is proper timing—taking antacids at least 2 hours apart from digoxin.
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