When educating a patient about Lorazepam (Ativan), the nurse should advise against the concurrent use of which substance?

Vitamin C supplements

Caffeinated beverages

Alcohol

Dairy products

Answer and Explanation

The Correct Answer is C

Choice A reason: Vitamin C supplements are not a concern for the concurrent use with Lorazepam, which is a medication that reduces anxiety and insomnia by enhancing the effects of a neurotransmitter called gammaaminobutyric acid (GABA) in the brain¹. Vitamin C is an essential nutrient that supports the immune system and the synthesis of collagen, a protein that forms the connective tissue in the body. Vitamin C does not interact with Lorazepam or affect its metabolism or clearance.

Choice B reason: Caffeinated beverages are not a concern for the concurrent use with Lorazepam, but they may reduce its effectiveness or cause unwanted effects. Caffeine is a stimulant that increases the activity of the central nervous system and counteracts the sedative and calming effects of Lorazepam. Caffeine may also cause side effects such as nervousness, insomnia, or palpitations, especially in high doses or in sensitive individuals. The nurse should advise the patient to limit or avoid caffeine intake while taking Lorazepam, and to monitor their response to the medication.

Choice C reason: Alcohol is a concern for the concurrent use with Lorazepam, as it can increase the risk of serious and potentially fatal side effects. Alcohol is a depressant that slows down the activity of the central nervous system and enhances the effects of Lorazepam. Alcohol can cause additive effects such as excessive sedation, respiratory depression, coma, or death when taken with Lorazepam. The nurse should advise the patient to avoid alcohol consumption while taking Lorazepam, and to seek immediate medical attention if they experience any signs of overdose or toxicity.

Choice D reason: Dairy products are not a concern for the concurrent use with Lorazepam, as they do not affect its absorption, distribution, metabolism, or excretion. Dairy products are a source of calcium, protein, and other nutrients that support the bone health and the muscle function. Dairy products do not interact with Lorazepam or alter its pharmacokinetics or pharmacodynamics.

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Correct Answer is A

Explanation

Choice A reason: This is correct. The kidneys are the main organs for excreting water-soluble substances, including most drugs and their metabolites. The kidneys filter the blood and remove waste products and excess fluid as urine. Drugs can be excreted by glomerular filtration, tubular secretion, or tubular reabsorption.

Choice B reason: This is incorrect. The pancreas is not involved in excretion of drugs. The pancreas is an organ that produces digestive enzymes and hormones, such as insulin and glucagon.

Choice C reason: This is incorrect. The gallbladder is not involved in excretion of drugs. The gallbladder is an organ that stores and concentrates bile, a fluid that helps digest fats.

Choice D reason: This is incorrect. The liver is not primarily responsible for excretion of drugs, although it plays an important role in drug metabolism. The liver is an organ that performs many functions, such as detoxifying substances, synthesizing proteins, and producing bile. The liver can transform drugs into more polar and water-soluble compounds, which can then be excreted by the kidneys or the biliary system.

A. You may experience increased urination as the medication takes effect. B. Rise slowly from sitting or lying positions to reduce the risk of dizziness. C. Be sure to take this medication on an empty stomach. D. You can expect to experience weight gain due to fluid retention.

Correct Answer is B

Explanation

Choice A reason: This is incorrect. Lisinopril is an angiotensin converting enzyme (ACE) inhibitor that lowers blood pressure and reduces the workload of the heart. It does not have a diuretic effect, meaning it does not increase urination.
Choice B reason: This is correct. Lisinopril can cause orthostatic hypotension, which is a sudden drop in blood pressure when changing positions. This can lead to dizziness, fainting, or falls. To prevent this, the nurse should instruct the client to rise slowly from sitting or lying positions and to avoid sudden movements.
Choice C reason: This is incorrect. Lisinopril can be taken with or without food. Taking it on an empty stomach does not improve its effectiveness or reduce its side effects.
Choice D reason: This is incorrect. Lisinopril does not cause weight gain due to fluid retention. In fact, it can help reduce edema, which is swelling caused by excess fluid in the body.

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When educating a patient about Lorazepam (Ativan), the nurse should advise against the concurrent use of which substance?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

Which organ is primarily responsible for excretion of a medication?

Correct Answer is A

Explanation

Which of the following instructions should a nurse give to a client who is starting lisinopril?

Correct Answer is B

Explanation

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