Which of the following instructions should a nurse give to a client who is starting lisinopril?

Choice A reason: This is correct. Blood pressure is the most important vital sign to monitor after giving sublingual nitroglycerin to a client with chest pain. Nitroglycerin is a medication that dilates the blood vessels and lowers the blood pressure. This can relieve the chest pain caused by angina, which is a condition where the heart muscle does not get enough oxygen due to narrowed or blocked arteries. However, if the blood pressure drops too low, the client may experience dizziness, fainting, or shock. Therefore, the nurse should check the blood pressure before and after giving nitroglycerin and report any significant changes to the doctor.

Choice B reason: This is incorrect. Blood glucose levels are not directly affected by sublingual nitroglycerin. However, some clients with chest pain may also have diabetes, which is a risk factor for heart disease. Diabetes is a condition where the body cannot regulate the amount of sugar in the blood. High or low blood sugar levels can cause symptoms such as thirst, hunger, fatigue, blurred vision, or confusion. Therefore, the nurse should check the blood glucose levels of clients with diabetes and follow the doctor's orders for managing their blood sugar.

Choice C reason: This is incorrect. Body temperature is not directly affected by sublingual nitroglycerin. However, some clients with chest pain may also have a fever, which is a sign of infection or inflammation. Fever is a condition where the body's temperature rises above the normal range. Fever can cause symptoms such as sweating, chills, headache, or muscle ache. Therefore, the nurse should check the body temperature of clients with fever and follow the doctor's orders for treating their infection or inflammation.

Choice D reason: This is incorrect. Respiratory rate is not directly affected by sublingual nitroglycerin. However, some clients with chest pain may also have difficulty breathing, which is a sign of heart failure or lung disease. Difficulty breathing is a condition where the client cannot get enough air into or out of the lungs. Difficulty breathing can cause symptoms such as coughing, wheezing, or gasping. Therefore, the nurse should check the respiratory rate of clients with difficulty breathing and follow the doctor's orders for improving their oxygenation.

Choice A reason: This is incorrect. Distributing the doses evenly throughout the day may increase the risk of daytime sedation and impair the client's ability to perform daily activities. Diphenhydramine is a sedating antihistamine that causes drowsiness and reduces alertness.

Choice B reason: This is correct. Taking most of the daily dose at bedtime may minimize daytime sedation and help the client sleep better at night. Diphenhydramine is often used as a short-term treatment for insomnia.

Choice C reason: This is incorrect. Taking the medication with meals does not affect the sedative effect of diphenhydramine. It may only reduce the risk of stomach upset, which is not a common side effect of diphenhydramine.

Choice D reason: This is incorrect. Gradually decreasing the dose once tolerance to the effect is reached may not be advisable, as it may reduce the effectiveness of the medication for relieving pruritus. Diphenhydramine is an antihistamine that blocks the action of histamine, a chemical that causes itching and inflammation in allergic reactions.