When describing the differences affecting the pharmacokinetics of drugs administered to children, which would the nurse include?

A. Absorption of drugs administered by subcutaneous injection is increaseD. Subcutaneous absorption can vary based on factors such as blood flow and tissue characteristics, but it is generally slower and more variable compared to intramuscular absorption.

B. Absorption of intramuscularly administered drugs is fairly constant: Intramuscular absorption tends to be more consistent compared to subcutaneous absorption. However, absorption rates can still be affected by factors such as muscle mass and blood flow.

C. Topical drugs are absorbed more quickly in young children than adults: Topical drug absorption can be influenced by factors such as skin thickness and permeability, but absorption rates may not necessarily be faster in young children compared to adults.

D. Oral drugs are absorbed more quickly in children than adults: This statement is generally incorrect. While gastrointestinal transit time may be faster in children, other factors such as

gastric pH and enzymatic activity can affect oral drug absorption, and absorption rates may not always be faster in children compared to adults.

To calculate the total fluid intake, add up the volume of each item consumed:
- 1⁄2 cup of juice = approximately 120 mL
- 3 oz gelatin = approximately 90 mL
- 1 oz of an ice pop = approximately 30 mL
- 20 mL ginger ale
Total fluid intake = 120 mL (juice) + 90 mL (gelatin) + 30 mL (ice pop) + 20 mL (ginger ale)
= 260 mL