What is a major difference between rheumatoid arthritis and osteoarthritis?

A. Nausea. Disulfiram causes an acute sensitivity to alcohol. When alcohol is consumed, it leads to an accumulation of acetaldehyde, causing unpleasant effects like severe nausea, vomiting, and headache, deterring the individual from drinking.
B. Blackouts. Blackouts are periods of memory loss due to heavy drinking but are not specifically induced by the combination of disulfiram and alcohol.
C. Hypertension. While disulfiram can cause cardiovascular effects, hypertension is not the primary or most severe side effect of consuming alcohol while on disulfiram.
D. Headaches. Headaches are indeed a part of the disulfiram-alcohol reaction, but the primary severe side effect leading to the aversion is nausea.

A. Weekly for at least 6 months, then decrease the dose to once a month: Methadone is typically administered daily, not weekly, to maintain stable blood levels and manage withdrawal symptoms effectively.
B. Daily until stabilized, then gradually reduce the dose to zero. Methadone is usually given daily to stabilize the patient. Once stabilized, the dose is gradually tapered off to prevent withdrawal symptoms and reduce dependence.
C. Monthly for 6 to 10 months, then decrease the dose to zero. Methadone treatment requires daily dosing for effective management, not monthly.
D. Daily for the rest of his life. While some patients may require long-term maintenance on methadone, the goal is usually to taper off the dose gradually if possible.