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Unlike heparin, the anticoagulant activity of warfarin can take several

to reach its maximum effect.
Answer and Explanation

The Correct Answer is {"dropdown-group-1":"B"}

A. Minutes: This is too short a timeframe for warfarin's effect. It takes longer for the body's existing clotting factors to be depleted.

B. Days: This medication works by inhibiting the production of vitamin K-dependent clotting factors in the liver. As existing clotting factors are used up and new ones aren't produced as efficiently, it takes time for the anticoagulant effect to become significant.

C. Weeks: While the full effect might take some time (around 3-5 days), several weeks is an overestimation for most patients.

D. Hours: A few hours might show some initial effect, but it's not enough time for a substantial anticoagulant effect. It usually takes at least a day or two.


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Related Questions

Correct Answer is D

Explanation

A. Temperature of 100.8 Degrees Fahrenheit (38.2 Degrees Celsius): Fever can indicate a potential adverse reaction to the medication or may be a sign of infection, which could complicate the patient's condition. While a fever can be a sign of an infection, it's not a typical adverse effect for alteplase

B. Skin rash with urticaria: Skin rash and urticaria (hives) can indicate an allergic reaction to alteplase. Allergic reactions can range from mild to severe and may necessitate discontinuation of the medication and administration of appropriate treatment, such as antihistamines or corticosteroids, depending on the severity of the reaction but it's less common than bleeding.

C. Wheezing with labored breathing: Wheezing and labored breathing can indicate a severe allergic reaction or anaphylaxis to alteplase but again, bleeding is a more prominent concern.

D. Bruising and epistaxis: Alteplase increases the risk of bleeding due to its thrombolytic activity. Bruising and epistaxis (nosebleeds) are common manifestations of bleeding associated with alteplase therapy. Monitoring for these signs helps detect potential bleeding complications early, allowing for prompt intervention to minimize further bleeding and manage the patient's condition appropriately.

Correct Answer is C

Explanation

  1. White Blood Cell Count (WBC): WBCs are part of the immune system and play a role in fighting infections. However, they are not directly involved in hemostasis or clot formation. WBCs do not adhere to the vessel wall during hemostasis.
  2. Activated Partial Thromboplastin Time (aPTT): aPTT measures the time it takes for blood to clot. It is primarily used to monitor heparin therapy, not warfarin. aPTT is not specific for warfarin monitoring.
  3. Prothrombin Time (PT): PT measures how quickly blood clots. It is used to monitor warfarin therapy and assess clotting factors. PT is essential for monitoring warfarin effectiveness.
  4. Platelet Count: Platelets are crucial for clot formation. Platelet count helps assess platelet function. Platelets play a direct role in hemostasis.

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