The U.S. Food and Drug Administration has issued a warning for users of antiepileptic drugs.
Based on this report, the nurse will monitor for which potential problems with this class of drugs?
Signs of bone marrow depression
Increased risk of suicidal thoughts and behaviors
Increased risk of cardiovascular events, such as strokes
Indications of drug addiction and dependency
The Correct Answer is B
A. Signs of bone marrow depression are not typically associated with antiepileptic drugs. This adverse effect is more commonly seen with medications such as chemotherapy agents.
B. Increased risk of suicidal thoughts and behaviors is a well-documented concern with antiepileptic drugs, particularly when used for psychiatric indications or in certain patient populations. The FDA has issued warnings regarding this risk, and healthcare providers should monitor patients for changes in mood, behavior, and suicidal ideation.
C. While some antiepileptic drugs may have cardiovascular effects, such as prolongation of the QT interval, the FDA warning specifically highlights the risk of suicidal thoughts and behaviors rather than cardiovascular events like strokes.
D. Indications of drug addiction and dependency are not typically associated with antiepileptic drugs. These medications are not central nervous system depressants and do not produce the euphoria or withdrawal symptoms characteristic of addictive substances.
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Related Questions
Correct Answer is B
Explanation
A. Dobutamine is a sympathomimetic drug used to increase cardiac output in conditions such as heart failure. It is not an antidote for cholinergic drug overdose.
B. Atropine sulfate is the antidote for cholinergic drug overdose. It acts as a competitive antagonist to acetylcholine at muscarinic receptors, counteracting the effects of excessive cholinergic stimulation.
C. Atenolol is a beta-blocker used to manage hypertension and certain cardiac conditions. It is not an antidote for cholinergic drug overdose.
D. Bethanechol is a cholinergic agonist used to stimulate bladder contractions in urinary retention. It is not an antidote for cholinergic drug overdose; in fact, it would exacerbate cholinergic effects.
Correct Answer is A
Explanation
A. Partial agonists like nalbuphine have a lower dependency potential than full agonists. This means they are less likely to lead to physical dependence or tolerance when used for pain
management.
B. Partial agonists do not necessarily have a higher potency than agonists. Potency refers to the dose of a drug required to produce a specific effect, which can vary among different drugs regardless of their classification as agonists or partial agonists.
C. Partial agonists like nalbuphine are not typically used for their anti-inflammatory effects.
They are primarily used for pain management.
D. Partial agonists like nalbuphine are not typically used to reverse the effects of opiates. They may be used in certain situations to manage opioid-induced side effects or in cases of opioid overdose, but their primary indication is for pain management.
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