The patient needs both regular insulin and NPH insulin to be administered subcutaneously. The nurse will mix both insulins in the same syringe.
What is the correct technique for preparing this insulin order?
Draw up one-half of the NPH insulin followed by one-half of the regular insulin and repeat.
Draw up one-half of the regular insulin followed by one-half of the NPH insulin and repeat.
Draw up the NPH insulin into the insulin syringe followed by the regular insulin.
Draw up the regular insulin into the insulin syringe followed by the NPH insulin.
The Correct Answer is D
The correct technique for preparing this insulin order is to follow these steps¹²:
- Perform hand hygiene and put on gloves.
- Mix NPH (cloudy) insulin by gently rotating the vial between the palms of your hands. Do not shake the vial.
- Clean the tops of both vials with alcohol swabs and let them dry.
- Draw up the amount of air equal to the dose of NPH insulin into a syringe. Inject the air into the NPH vial without touching the needle to the solution. Withdraw the needle and syringe without drawing up any insulin. This will create positive pressure in the NPH vial and make it easier to draw up later.
- Draw up the amount of air equal to the dose of regular (clear) insulin into the same syringe. Inject the air into the regular vial and invert the vial. Make sure the needle tip is below the fluid level and draw up slightly more than the dose of regular insulin. Tap the syringe gently to remove any air bubbles and push out any excess insulin to get the exact dose. Withdraw the needle and syringe from the regular vial.
- Reinsert the needle and syringe into the NPH vial without touching the needle to the solution. Invert the vial and draw up slightly more than the dose of NPH insulin. Tap the syringe gently to remove any air bubbles and push out any excess insulin to get the exact dose. Withdraw the needle and syringe from the NPH vial.
- Check that you have the correct doses of both insulins in one syringe. The total volume should be equal to the sum of both doses.
- Administer the dose within 5 to 10 minutes after drawing up because regular insulin binds to NPH and this decreases its action.

Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
To answer this question, we need to calculate the infusion rate in mL per hour, then multiply it by the total time in hours, and finally divide it by 1000 to get the volume in litres.
The infusion rate in mL per hour is the amount of fluid that is given to a patient over a period of time. It can be calculated by dividing the total volume of fluid in mL by the total time in hours². In this case, the infusion rate is:
2.75 mL/min × 60 min/h = 165 mL/h
The total volume of fluid in mL is the infusion rate multiplied by the total time in hours. In this case, the total volume is:
165 mL/h × 7 h = 1155 mL
The volume in litres is the volume in mL divided by 1000. In this case, the volume in litres is:
1155 mL / 1000 = 1.16 L
Therefore, the correct answer is d. 1.16 L.
Correct Answer is A
Explanation
To find how much medication to administer, you need to calculate the following:
- The volume of diphenhydramine in milliliters
- The infusion time in minutes
First, divide the dose of diphenhydramine by the concentration to get the volume in milliliters:
25 mg / 50 mg/mL = 0.5 mL diphenhydramine should be diluted in 10 to 20 mL of normal saline and infused over at least 2 minutes.
Therefore, the nurse should administer **0.5 mL** of diphenhydramine diluted in 10 to 20 mL of normal saline over **at least 2 minutes**.
The nurse should administer this medication **as soon as possible** after receiving the order and the medication from the pharmacy, as STAT means immediately or urgently. The nurse should also monitor the client for signs of improvement or adverse reactions.
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