The patient is taking low-dose aspirin daily for his heart. The nurse knows only a portion of the medication taken actually reaches the tissue due to what process?
Distribution
First-pass effect
Reduced absorption
Gastrointestinal circulation
The Correct Answer is B
A. Distribution refers to the movement of the drug from the bloodstream into tissues and organs, but it does not explain why only a portion of the medication reaches the tissues.
B. The first-pass effect occurs when an orally administered drug is metabolized by the liver before reaching systemic circulation. Aspirin, when taken orally, undergoes significant metabolism in the liver, reducing the amount of active drug available to exert its therapeutic effect. This explains why only a portion of the drug reaches the tissues.
C. Reduced absorption can limit drug availability, but aspirin is generally well absorbed in the gastrointestinal tract. The primary reason for reduced drug availability in this case is metabolism by the liver, not poor absorption.
D. Gastrointestinal circulation involves the enterohepatic recycling of some drugs, but it does not explain why only a portion of aspirin reaches systemic circulation. The first-pass effect is the primary factor.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
a) Encouraging self-application is beneficial in some cases, but it is not always appropriate. The nurse must ensure the medication is applied correctly and safely, especially if the patient has mobility or cognitive impairments.
b) Wearing treatment gloves is important when handling certain medications, but it is not required for all topical applications. Some medications, such as nitroglycerin ointment, require gloves to prevent nurse exposure, but others do not.
c) Changing gloves between skin preparation and medication application is not a universal requirement. In most cases, the same pair of gloves can be used unless contamination occurs.
d) Performing effective hand hygiene before and after applying the medication is the most essential action to prevent infection and cross-contamination.
Correct Answer is A
Explanation
A. The FDA is responsible for regulating and ensuring the safety and efficacy of drugs, medical devices, and other health-related products. All medications must undergo rigorous scientific testing and approval processes overseen by the FDA before they can be marketed to the public.
B. The DEA regulates controlled substances and enforces laws related to drug abuse, but it does not control the scientific testing of medications.
C. The CDC focuses on public health and disease prevention, not the regulation or testing of medications.
D. The Joint Commission accredits healthcare organizations but does not directly oversee the scientific testing of medications.
Whether you are a student looking to ace your exams or a practicing nurse seeking to enhance your expertise , our nursing education contents will empower you with the confidence and competence to make a difference in the lives of patients and become a respected leader in the healthcare field.
Visit Naxlex, invest in your future and unlock endless possibilities with our unparalleled nursing education contents today
Report Wrong Answer on the Current Question
Do you disagree with the answer? If yes, what is your expected answer? Explain.
Kindly be descriptive with the issue you are facing.