The nurse understands that the length of time needed for a drug to reach the minimum effective concentration (MEC) is the

Duration of action.

Onset of action.

Peak action time.

Time response curve.

Answer and Explanation

The Correct Answer is B

A. Duration of action refers to the length of time a drug remains effective after reaching the MEC, but it does not describe the time required to reach this threshold.

B. Onset of action is the time it takes for a drug to reach the minimum effective concentration (MEC) and begin producing a therapeutic effect. This is influenced by factors such as drug absorption and distribution.

C. Peak action time refers to the time at which the drug reaches its highest concentration in the bloodstream, not the time required to reach the MEC.

D. The time response curve is a graphical representation of a drug's effects over time but does not specifically define the time needed to reach the MEC.

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Correct Answer is D

Explanation

a) Phase I studies focus on assessing the safety, dosing, and side effects of a drug in healthy volunteers, not its clinical effectiveness or potential new uses.

b) Phase II studies evaluate the drug's effectiveness and safety in a small group of patients with the targeted condition but do not focus on potential new uses.

c) Phase III studies are large-scale trials conducted to confirm the drug's effectiveness and safety before approval but do not typically involve studying new uses of the drug.

d) Phase IV studies occur after a drug has been approved and marketed. These studies, often called post-marketing surveillance, evaluate the drug's effectiveness and safety in the general population and investigate new potential uses or long-term effects.

A. Lung function B. Kidney function C. Liver function D. Route of administration

Correct Answer is C

Explanation

a) Lung function primarily affects gas exchange and respiratory function but does not significantly influence drug absorption.

b) Kidney function is important for drug excretion rather than absorption. It impacts drug elimination and toxicity risk rather than how well a drug is absorbed.

c) Liver function plays a key role in drug metabolism. Poor liver function can alter drug absorption and metabolism, particularly for orally administered drugs that undergo the first-pass effect.

d) The route of administration directly impacts drug absorption. For example, intravenous (IV) drugs bypass absorption entirely, while oral medications must go through the digestive system before entering circulation.

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The nurse understands that the length of time needed for a drug to reach the minimum effective concentration (MEC) is the

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

Before marketing a new drug that has been approved for use based on clinical effectiveness and safety, the manufacturer wishes to study the potential new uses for the drug. This is an example of which phase of study?

Correct Answer is D

Explanation

What factors can influence drug absorption? (Select all that apply)

Correct Answer is C

Explanation

A nurse is instructing a pregnant patient concerning the potential risk to her fetus from a Pregnancy Category B drug. The nurse would inform the patient that:

The nurse is preparing to give a medication to a child. The child's parent asks whether the drug is safe for children. How will the nurse respond to the parent?

When involved in phase III drug evaluation studies, which responsibilities would the nurse have?

The nurse is caring for an older adult patient who is receiving multiple medications. When monitoring this patient for potential drug toxicity, the nurse should review which lab values closely?

The nurse understands that the length of time needed for a drug to reach the minimum effective concentration (MEC) is the

The nurse is developing a teaching plan for an elderly patient who will begin taking an antihypertensive drug that causes dizziness and orthostatic hypotension. Which nursing diagnosis is appropriate for this patient?

A nurse is administering medication at the bedside. Which of the following actions should be the first priority?

The nurse is caring for a patient who is receiving a high dose of intravenous azithromycin to treat an infection. The patient is also taking acetaminophen for pain. The nurse should expect to review which lab values when monitoring for this drug side effects?