When involved in phase III drug evaluation studies, which responsibilities would the nurse have?

Monitor and observe clients closely for adverse effects

Work with animals which are given experimental drugs

Make decisions that will determine the effectiveness of the drug

Select appropriate clients to be involved in the drug study

Answer and Explanation

The Correct Answer is A

a) Phase III clinical trials involve large groups of human participants and focus on confirming the drug's effectiveness and monitoring for adverse effects. The nurse plays a key role in observing and documenting any side effects experienced by the patients.

b) Working with animals is part of preclinical trials, not phase III studies. By the time a drug reaches phase III, it has already undergone animal testing.

c) While data collected in phase III trials contribute to determining a drug’s effectiveness, the decision-making is primarily done by researchers and regulatory agencies, not individual nurses.

d) Selection of appropriate clients for a drug study is generally determined by researchers and trial coordinators based on inclusion and exclusion criteria, rather than by nurses directly.

Nursing Test Bank

Quiz #1: RN Exams Pharmacology Exams Quiz #2: RN Exams Medical-Surgical Exams Quiz #3: RN Exams Fundamentals Exams Quiz #4: RN Exams Maternal-Newborn Exams Quiz #5: RN Exams Anatomy and Physiology Exams Quiz #6: RN Exams Obstetrics and Pediatrics Exams Quiz #7: RN Exams Fluid and Electrolytes Exams Quiz #8: RN Exams Community Health Exams Quiz #9: RN Exams Promoting Health across the lifespan Exams Quiz #10: RN Exams Multidimensional care Exams

Get 100+ Naxlex Exit Exams for $79 Try Naxlex NCLEX-RN (14 Day Free-Trial)

Naxlex Comprehensive Predictor Exams

Quiz #1: Naxlex RN Comprehensive online practice 2019 B with NGN Quiz #2: Naxlex RN Comprehensive Predictor 2023 Quiz #3: Naxlex RN Comprehensive Predictor 2023 Exit Exam A Quiz #4: Naxlex HESI Exit LPN Exam Quiz #5: Naxlex PN Comprehensive Predictor PN 2020 Quiz #6: Naxlex VATI PN Comprehensive Predictor 2020 Quiz #8: Naxlex PN Comprehensive Predictor 2023 - Exam 1 Quiz #10: Naxlex HESI PN Exit exam Quiz #11: Naxlex HESI PN EXIT Exam 2

Free Nursing Study Resources

Correct Answer is C

Explanation

a) Lung function primarily affects gas exchange and respiratory function but does not significantly influence drug absorption.

b) Kidney function is important for drug excretion rather than absorption. It impacts drug elimination and toxicity risk rather than how well a drug is absorbed.

c) Liver function plays a key role in drug metabolism. Poor liver function can alter drug absorption and metabolism, particularly for orally administered drugs that undergo the first-pass effect.

d) The route of administration directly impacts drug absorption. For example, intravenous (IV) drugs bypass absorption entirely, while oral medications must go through the digestive system before entering circulation.

A. Decreased drug effects. B. Increased drug effects. C. Decreased therapeutic range. D. Increased therapeutic range.

Correct Answer is B

Explanation

a) Decreased drug effects are unlikely in liver disease because impaired liver function reduces drug metabolism, leading to higher drug concentrations in the bloodstream.

b) Increased drug effects occur because the liver is responsible for metabolizing many drugs. In liver disease, drug metabolism is slowed, leading to prolonged drug action and potential toxicity.

c) Decreased therapeutic range is not the primary concern. The therapeutic range refers to the safe and effective drug concentration, but liver disease mainly affects drug metabolism and clearance.

d) Increased therapeutic range is incorrect because liver disease does not widen the range of safe drug levels; instead, it increases the risk of drug accumulation and toxicity.

View Question and Answer

Whether you are a student looking to ace your exams or a practicing nurse seeking to enhance your expertise , our nursing education contents will empower you with the confidence and competence to make a difference in the lives of patients and become a respected leader in the healthcare field.

Visit Naxlex, invest in your future and unlock endless possibilities with our unparalleled nursing education contents today

When involved in phase III drug evaluation studies, which responsibilities would the nurse have?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

What factors can influence drug absorption? (Select all that apply)

Correct Answer is C

Explanation

The nurse gives medication to a patient with a history of liver disease. The nurse will monitor this patient for

Correct Answer is B

Explanation

A family member expresses concern that a patient is taking several herbal remedies and worries that they may be unsafe. The nurse will respond by saying that herbs

The patient is taking low-dose aspirin daily for his heart. The nurse knows only a portion of the medication taken actually reaches the tissue due to what process?

When the nurse practices the six rights of medication, what does it ensure?

The nurse is caring for an older adult patient who is receiving multiple medications. When monitoring this patient for potential drug toxicity, the nurse should review which lab values closely?

The nurse is preparing to administer a schedule II injectable drug and is drawing up half of the contents of a single-use vial. Which nursing action is correct?

What is the responsibility of the nurse related to the patient's drug therapy? (Select all that apply.)

A clinical drug trial is conducting a study of pharmacokinetics and safety of a drug in healthy individuals. The nurse will assist enrollment of participants into the next phase of the study and will include which subject?