The nurse is caring for a client with renal dysfunction who requires an oral antidiabetic agent.
What drug will the nurse expect to see ordered?
Tolbutamide.
Tolazamide.
Chlorpropamide.
Chlorpromazine.
The Correct Answer is A
Tolbutamide is preferred for clients with renal dysfunction, who may not be able to excrete chlorpropamide, because it is more easily cleared from the body.
Choice B. Tolazamide is wrong because it is a first-generation sulfonylurea that is used less frequently and is usually tried after tolbutamide and chlorpropamide have been shown to be ineffective.
Choice C. Chlorpropamide is wrong because it is a first-generation sulfonylurea that may accumulate in clients with renal dysfunction and cause hypoglycemia.
Choice D. Chlorpromazine is wrong because it is an antipsychotic agent, not an oral antidiabetic agent.
First-generation sulfonylureas are oral antidiabetic agents that stimulate insulin secretion from the pancreas.
They are used to treat type 2 diabetes mellitus.
The normal range of blood glucose level is 70 to 110 mg/dL.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
It works by relaxing the smooth muscles of the airways and increasing airflow to the lungs.
However, theophylline has a narrow therapeutic range and can cause side effects such as nausea, vomiting, insomnia, tremors, and cardiac arrhythmias if the blood level is too high.
Caffeine is a stimulant that can increase the effects of theophylline and raise the risk of toxicity.
Therefore, patients taking theophylline should avoid caffeine-containing beverages such as coffee, tea, cola, and energy drinks.
Choice A is wrong because eating foods high in potassium has no effect on theophylline metabolism or action.
Potassium is an electrolyte that is important for nerve and muscle function, but it does not interact with theophylline.
Choice C is wrong because taking the medication on an empty stomach can increase the absorption of theophylline and cause gastric irritation.
Theophylline should be taken with food or milk to reduce stomach upset and prevent fluctuations in blood levels.
Choice D is wrong because limiting fluid intake to 1,000 mL a day can cause dehydration and increase the concentration of theophylline in the blood.
Theophylline
Correct Answer is B
Explanation
The nurse should caution the student to avoid using alcohol with trimethobenzamide because this combination can cause side effects such as drowsiness, dizziness, and impaired reactions. Alcohol can also worsen the symptoms of nausea and vomiting.
Choice A is wrong because St.
John’s wort is a herbal supplement that is used to treat depression and anxiety.
It does not interact with trimethobenzamide.
Choice C is wrong because calcium channel blockers are a class of medications that are used to treat high blood pressure and heart problems.
They do not interact with trimethobenzamide.
Choice D is wrong because selective serotonin reuptake inhibitors (SSRIs) are a class of medications that are used to treat depression and anxiety.
They do not interact with trimethobenzamide.
Trimethobenzamide is an antihistamine that works by blocking the D receptor in the brain and suppressing the chemoreceptor trigger zone that causes nausea and vomiting.
It is available as an oral capsule or an intramuscular injection.
It can cause side effects such as skin rash, tremors, parkinsonism, and jaundice.
It should not be used in children or people with liver or kidney disease.
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