The nurse is caring for a client with renal dysfunction who requires an oral antidiabetic agent.
What drug will the nurse expect to see ordered?

Tolbutamide.

Tolazamide.

Chlorpropamide.

Chlorpromazine.

Answer and Explanation

The Correct Answer is A

Tolbutamide is preferred for clients with renal dysfunction, who may not be able to excrete chlorpropamide, because it is more easily cleared from the body.

Choice B. Tolazamide is wrong because it is a first-generation sulfonylurea that is used less frequently and is usually tried after tolbutamide and chlorpropamide have been shown to be ineffective.

Choice C. Chlorpropamide is wrong because it is a first-generation sulfonylurea that may accumulate in clients with renal dysfunction and cause hypoglycemia.

Choice D. Chlorpromazine is wrong because it is an antipsychotic agent, not an oral antidiabetic agent.

First-generation sulfonylureas are oral antidiabetic agents that stimulate insulin secretion from the pancreas.

They are used to treat type 2 diabetes mellitus.

The normal range of blood glucose level is 70 to 110 mg/dL.

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Correct Answer is A

Explanation

Loratadine is a second-generation antihistamine that does not cause drowsiness or sedation as a common side effect. It can relieve the symptoms of seasonal rhinitis such as sneezing, runny nose, and itching.

Choice B. Diphenhydramine is wrong because it is a first-generation antihistamine that can cause drowsiness or sedation as a common side effect.

It can also cause dry mouth, blurred vision, and urinary retention.

Choice C. Hydroxyzine is wrong because it is also a first-generation antihistamine that can cause drowsiness or sedation as a common side effect.

It can also cause dry mouth, blurred vision, and urinary retention.

It is mainly used for anxiety and itching.

Choice D. Dexchlorphen

A. A client being treated for a traumatic brain injury. B. A client with a history of ischemic heart disease. C. A pediatric client. D. A client with type 2 diabetes.

Correct Answer is A

Explanation

This is because phenothiazines are contraindicated in patients with suspected or established subcortical brain damage. Phenothiazines can cause central nervous system effects such as drowsiness, dizziness, and extrapyramidal symptoms that may worsen the condition of a client with a brain injury.

Choice B is wrong because phenothiazines are not contraindicated in clients with ischemic heart disease.

However, they should be used with caution as they can cause hypotension and cardiac arrhythmias.

Choice C is wrong because phenothiazines are not contraindicated in pediatric clients.

However, they should be used with caution as they can cause sedation, anticholinergic effects, and paradoxical excitement.

Choice D is wrong because phenothiazines are not contraindicated in clients with type 2 diabetes.

However, they should be used with caution as they can cause hyperglycemia and alter the effects of antidiabetic drugs.

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The nurse is caring for a client with renal dysfunction who requires an oral antidiabetic agent. What drug will the nurse expect to see ordered?

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Naxlex Comprehensive Predictor Exams

A client has an important presentation to make in 4 hours, and he needs relief from the congestion of seasonal rhinitis. The client calls the nurse, explains the situation, and tells the nurse that he cannot afford to be drowsy. What medication is most likely to meet this client’s needs?

Correct Answer is A

Explanation

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Correct Answer is A

Explanation

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The nurse is caring for a client with renal dysfunction who requires an oral antidiabetic agent.
What drug will the nurse expect to see ordered?