The nurse is caring for a client with renal dysfunction who requires an oral antidiabetic agent.
What drug will the nurse expect to see ordered?
Tolbutamide.
Tolazamide.
Chlorpropamide.
Chlorpromazine.
The Correct Answer is A
Tolbutamide is preferred for clients with renal dysfunction, who may not be able to excrete chlorpropamide, because it is more easily cleared from the body.
Choice B. Tolazamide is wrong because it is a first-generation sulfonylurea that is used less frequently and is usually tried after tolbutamide and chlorpropamide have been shown to be ineffective.
Choice C. Chlorpropamide is wrong because it is a first-generation sulfonylurea that may accumulate in clients with renal dysfunction and cause hypoglycemia.
Choice D. Chlorpromazine is wrong because it is an antipsychotic agent, not an oral antidiabetic agent.
First-generation sulfonylureas are oral antidiabetic agents that stimulate insulin secretion from the pancreas.
They are used to treat type 2 diabetes mellitus.
The normal range of blood glucose level is 70 to 110 mg/dL.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
Loratadine is a second-generation antihistamine that does not cause drowsiness or sedation as a common side effect. It can relieve the symptoms of seasonal rhinitis such as sneezing, runny nose, and itching.
Choice B. Diphenhydramine is wrong because it is a first-generation antihistamine that can cause drowsiness or sedation as a common side effect.
It can also cause dry mouth, blurred vision, and urinary retention.
Choice C. Hydroxyzine is wrong because it is also a first-generation antihistamine that can cause drowsiness or sedation as a common side effect.
It can also cause dry mouth, blurred vision, and urinary retention.
It is mainly used for anxiety and itching.
Choice D. Dexchlorphen
Correct Answer is A
Explanation
Phenothiazines are contraindicated in patients with suspected or established subcortical brain damage. Phenothiazines are a class of drugs that have antipsychotic, antiemetic, and sedative effects. They act by blocking dopamine receptors in the brain and can cause extrapyramidal symptoms, hypotension, and anticholinergic effects.
Choice B is wrong because phenothiazines are not contraindicated in patients with ischemic heart disease.
However, they can cause orthostatic hypotension and cardiac arrhythmias, so they should be used with caution and monitored closely in these patients.
Choice C is wrong because phenothiazines are not contraindicated in pediatric patients.
However, they can cause sedation, hypotension, and extrapyramidal symptoms, so they should be used with caution and at lower doses in these patients.
Choice D is wrong because phenothiazines are not contraindicated in patients with type 2 diabetes.
However, they can cause hyperglycemia and weight gain, so they should be used with caution and monitored closely in these patients.
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