The nurse is caring for a client with renal dysfunction who requires an oral antidiabetic agent.
What drug will the nurse expect to see ordered?
Tolbutamide.
Tolazamide.
Chlorpropamide.
Chlorpromazine.
The Correct Answer is A
Tolbutamide is preferred for clients with renal dysfunction, who may not be able to excrete chlorpropamide, because it is more easily cleared from the body.
Choice B. Tolazamide is wrong because it is a first-generation sulfonylurea that is used less frequently and is usually tried after tolbutamide and chlorpropamide have been shown to be ineffective.
Choice C. Chlorpropamide is wrong because it is a first-generation sulfonylurea that may accumulate in clients with renal dysfunction and cause hypoglycemia.
Choice D. Chlorpromazine is wrong because it is an antipsychotic agent, not an oral antidiabetic agent.
First-generation sulfonylureas are oral antidiabetic agents that stimulate insulin secretion from the pancreas.
They are used to treat type 2 diabetes mellitus.
The normal range of blood glucose level is 70 to 110 mg/dL.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
Glycerin suppositories are safe and effective for infants with constipation. They work by lubricating and softening the stool, and stimulating the rectal muscles to contract.
Choice B is wrong because magnesium hydroxide is not recommended for infants under 6 months of age, and may cause diarrhea, electrolyte imbalance, or magnesium toxicity.
Choice Cis wrong because watchful waiting for 24 hours may not be enough to relieve the infant’s discomfort and may lead to further complications such as fecal impaction or dehydration.
Choice Dis wrong because feeding supplementation with free water may not be sufficient to treat constipation, and may dilute the infant’s intake of nutrients and electrolytes.
Correct Answer is A
Explanation
Octreotide is a synthetic analog of somatostatin, a hormone that inhibits the secretion of growth hormone, insulin, glucagon, and other hormones. Octreotide can cause gastrointestinal side effects such as abdominal pain, diarrhea, constipation, nausea, vomiting, and flatulence. These side effects are more common and severe with the oral route than with the injectable route.
Choice B is wrong because tinnitus, or ringing in the ears, is not a common or serious side effect of octreotide.
Choice C is wrong because alteration in consciousness is not a common or serious side effect of octreotide.
However, octreotide can affect blood glucose levels and cause hypoglycemia or hyperglycemia, which can lead to confusion, dizziness, fainting, seizures, or coma in severe cases.
Choice D is wrong because changes in vision are not a common or serious side effect of octreotide.
However, octreotide can cause rare but serious eye problems such as blurred vision, double vision, eye pain, or blindness due to optic nerve damage or retinal detachment.
These eye problems require immediate medical attention.
Normal ranges for blood glucose are 70 to 100 mg/dL (3.9 to 5.6 mmol/L) for fasting and less than 140 mg/dL (7.8 mmol/L) for postprandial.
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