The LPN/LVN is aware that the bioavailability of a drug is based on multiple factors. Which factor(s) would be included? Select all that apply.
molecular weight
fat or liquid solubility
depth of breathing
development of a fever
presence of food
Correct Answer : A,B,E
A. Molecular weight: Drugs with lower molecular weight tend to have higher bioavailability because they can more easily pass through biological membranes.
B. Fat or liquid solubility: Drugs that are fat-soluble can cross cell membranes more easily, affecting their bioavailability. Water-soluble drugs may require transport mechanisms, which can limit absorption.
C. Depth of breathing: The depth of breathing primarily affects the absorption of inhaled drugs, not the general bioavailability of orally or intravenously administered medications.
D. Development of a fever: While fever can affect drug metabolism, it doesn’t directly influence the bioavailability of a drug.
E. Presence of food: Food in the stomach can either enhance or inhibit drug absorption, depending on the drug’s characteristics. This directly impacts bioavailability.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
A. Call the health-care provider to see if intravenous fluids are needed: This is not usually necessary unless the patient has a condition that requires it. It's more important to ensure NPO status is maintained.
B. Increase fluid intake prior to midnight to make sure the patient remains hydrated: This could be done, but it is less important than ensuring the patient follows the NPO instructions.
C. Remove the patient's water pitcher at the bedside shortly before midnight: This is the correct answer. Removing the pitcher helps prevent the patient from accidentally drinking water and violating NPO status.
D. This is an example of a STAT order and should be documented in the patient's chart: NPO orders are not STAT orders; they are routine orders related to the preparation for a procedure.
Correct Answer is A
Explanation
A. Replacement: Hypothyroidism is typically treated with hormone replacement therapy, such as levothyroxine, to compensate for the deficient thyroid hormone.
B. Curative: There is no cure for hypothyroidism, so curative therapy is not applicable. Treatment focuses on managing symptoms through hormone replacement.
C. Prophylactic: Prophylactic medications are used to prevent disease or conditions. This is not applicable to the treatment of hypothyroidism.
D. Palliative: Palliative care focuses on relieving symptoms in serious illness without curing the disease. However, hypothyroidism is managed with replacement therapy, not palliative care.
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