The LPN/LVN is aware that the bioavailability of a drug is based on multiple factors. Which factor(s) would be included? Select all that apply.

molecular weight

fat or liquid solubility

depth of breathing

development of a fever

presence of food

Answer and Explanation

Correct Answer : A,B,E

A. Molecular weight: Drugs with lower molecular weight tend to have higher bioavailability because they can more easily pass through biological membranes.

B. Fat or liquid solubility: Drugs that are fat-soluble can cross cell membranes more easily, affecting their bioavailability. Water-soluble drugs may require transport mechanisms, which can limit absorption.

C. Depth of breathing: The depth of breathing primarily affects the absorption of inhaled drugs, not the general bioavailability of orally or intravenously administered medications.

D. Development of a fever: While fever can affect drug metabolism, it doesn’t directly influence the bioavailability of a drug.

E. Presence of food: Food in the stomach can either enhance or inhibit drug absorption, depending on the drug’s characteristics. This directly impacts bioavailability.

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Correct Answer is D

Explanation

A. Determining which medication needs a prescription for the patient to obtain. The DEA does not determine which medications require prescriptions; this is typically under the jurisdiction of the Food and Drug Administration (FDA).

B. Ensuring the patient taking a medication has an option for generic medications. This role is more aligned with the FDA, which oversees the approval of generic medications. The DEA does not handle generic medication options.

C. Providing specific requirements for the manufacture of generic medications. This is also a role of the FDA, not the DEA. The DEA focuses on controlled substances, not the specifics of generic drug manufacturing.

D. Indicating which medications are controlled substances and enforcing the laws. This accurately describes the role of the DEA. The DEA classifies controlled substances into schedules and enforces the laws related to the handling, prescribing, and dispensing of these drugs.

A. The patient complains of shortness of breath B. The patient reports feeling hot, and her face appears flushed. C. The patient states that she feels nauseated and has a headache. D. The patient complains of continued wakefulness and agitation.

Correct Answer is A

Explanation

A. The patient complains of shortness of breath: Shortness of breath is a hallmark symptom of an anaphylactic reaction. It indicates that the patient may be experiencing airway constriction, which is a medical emergency.

B. The patient reports feeling hot, and her face appears flushed: Flushing and a feeling of warmth can be early signs of an allergic reaction, but they are not specific to anaphylaxis. Other more severe symptoms would need to be present to diagnose anaphylaxis.

C. The patient states that she feels nauseated and has a headache: Nausea and headache are not typically associated with anaphylaxis. They may be side effects of the medication but are not indicative of an allergic reaction severe enough to cause anaphylaxis.

D. The patient complains of continued wakefulness and agitation: Continued wakefulness and agitation could be side effects of the sleeping pill but are not symptoms of an anaphylactic reaction. These symptoms do not require immediate emergency intervention like anaphylaxis would.

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The LPN/LVN is aware that the bioavailability of a drug is based on multiple factors. Which factor(s) would be included? Select all that apply.

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

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Explanation

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Correct Answer is A

Explanation

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