The healthcare provider (HCP) prescribes 1 liter of 0.9% sodium chloride, USP IV to be infused over 12 hours for a client. How many mL/hr should the nurse program the infusion pump to deliver?

(Enter numerical value only. If rounding is required, round to the nearest whole number.)

A. Excessive bruising: While statins can rarely affect platelet function, leading to bruising, this is not commonly associated with elevated creatine kinase (CK) levels. Bruising is more indicative of coagulation issues rather than muscle injury.

B. Muscle tenderness: Elevated CK levels in a client taking atorvastatin suggest muscle injury, such as myopathy or rhabdomyolysis. Muscle tenderness, pain, or weakness are hallmark symptoms of these conditions. Prompt assessment is crucial, as continued statin use in the presence of muscle damage can lead to serious complications, including kidney failure .

C. Nausea and vomiting: These symptoms are nonspecific and can result from various causes. While they may occur in rhabdomyolysis, they are not primary indicators and should be considered in the broader clinical context.

D. Peripheral edema: Swelling in the extremities is not a typical sign of statin-induced muscle injury. It is more commonly associated with cardiac, renal, or hepatic conditions.

A. Avoid driving or operating machinery: Drowsiness and dizziness can occur with atenolol, especially when initiating therapy, but these effects are usually mild. While it's reasonable to use caution initially, this is not the most critical teaching point compared to orthostatic safety.

B. Take a missed dose as soon as possible: Although this may seem helpful, patients should not double doses or take extra doses close together. If a significant amount of time has passed, the missed dose may need to be skipped to prevent bradycardia or hypotension.

C. Standing slowly when getting up from bed: Atenolol, a beta-blocker, can cause orthostatic hypotension, especially in older adults. Teaching the client to rise slowly helps reduce the risk of dizziness and falls, making this a high-priority safety instruction following discharge.

D. Avoid intake of alcoholic beverages: Alcohol may enhance the hypotensive effects of beta-blockers, but moderate consumption is not strictly contraindicated. This advice is relevant but less urgent than preventing injury from orthostatic hypotension.